The future of (radio)‐labeled compounds in research and development within the life science industry

V Derdau, CS Elmore, T Hartung… - Angewandte Chemie …, 2023 - Wiley Online Library
In this review the applications of isotopically labeled compounds are discussed and put into
the context of their future impact in the life sciences. Especially discussing their use in the …

Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

I Alberts, H Sari, C Mingels, A Afshar-Oromieh, T Pyka… - Cancer Imaging, 2023 - Springer
Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the
most significant advancements in nuclear medicine since the advent of multi-modality …

Long axial field-of-view PET/CT devices: are we ready for the technological revolution?

L Filippi, A Dimitrakopoulou-Strauss… - Expert Review of …, 2022 - Taylor & Francis
In last decades hybrid imaging, combining molecular and anatomical data in a unique,
synergistic approach, has thoroughly changed the face of medical diagnostics [1, 2]. In …

89Zr-immuno-PET using the anti-LAG-3 tracer [89Zr]Zr-BI 754111: demonstrating target specific binding in NSCLC and HNSCC

IHC Miedema, MC Huisman, GJC Zwezerijnen… - European journal of …, 2023 - Springer
Purpose Although lymphocyte activation gene-3 (LAG-3) directed therapies demonstrate
promising clinical anti-cancer activity, only a subset of patients seems to benefit and …

Quantitative PET-based biomarkers in lymphoma: getting ready for primetime

JP Alderuccio, RA Kuker, F Yang… - Nature Reviews Clinical …, 2023 - nature.com
The use of functional quantitative biomarkers extracted from routine PET–CT scans to
characterize clinical responses in patients with lymphoma is gaining increased attention …

Digital PET/CT with 18F-FACBC in early castration-resistant prostate cancer: our preliminary results

L Filippi, O Bagni, O Schillaci - Expert Review of Medical Devices, 2022 - Taylor & Francis
Background We assessed the role of digital PET/CT (dPET/CT) with 18F-FACBC in patients
affected by castration-resistant prostate cancer with PSA levels≤ 3 ng/mL (early CRPC), no …

Long axial field-of-view PET/CT could answer unmet needs in gynecological cancers

EKA Triumbari, V Rufini, C Mingels, A Rominger… - Cancers, 2023 - mdpi.com
Simple Summary Recent advances in PET/CT technology led to the development of long-
axial field-of-view (LAFOV) PET/CT with the possibility of simultaneously scanning a large …

Quantitation of dynamic total-body PET imaging: recent developments and future perspectives

F Gu, Q Wu - European Journal of Nuclear Medicine and Molecular …, 2023 - Springer
Background Positron emission tomography (PET) scanning is an important diagnostic
imaging technique used in disease diagnosis, therapy planning, treatment monitoring, and …

Total body PET/CT: a role in musculoskeletal diseases

S Katal, P Patel, J Lee, K Taubman… - Seminars in Nuclear …, 2024 - Elsevier
Recent advancements in PET technology have culminated in the development of total-body
PET (TB-PET) systems, which overcome many limitations of traditional scanners. These TB …

Photoredox nucleophilic (radio) fluorination of alkoxyamines

S Ortalli, J Ford, AA Trabanco, M Tredwell… - Journal of the …, 2024 - ACS Publications
Herein, we report a photoredox nucleophilic (radio) fluorination using TEMPO-derived
alkoxyamines, a class of substrates accessible in a single step from a diversity of readily …