Epstein–Barr virus latent genes

MS Kang, E Kieff - Experimental & molecular medicine, 2015 - nature.com
Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

Metacaspases

L Tsiatsiani, F Van Breusegem, P Gallois… - Cell Death & …, 2011 - nature.com
Metacaspases are cysteine-dependent proteases found in protozoa, fungi and plants and
are distantly related to metazoan caspases. Although metacaspases share structural …

[HTML][HTML] A pan-cancer analysis of the oncogenic role of staphylococcal nuclease domain-containing protein 1 (SND1) in human tumors

X Cui, X Zhang, M Liu, C Zhao, N Zhang, Y Ren, C Su… - Genomics, 2020 - Elsevier
Although emerging cell-or animal-based evidence supports the relationship between SND1
and cancers, no pan-cancer analysis is available. We thus first explored the potential …

A micrococcal nuclease homologue in RNAi effector complexes

AA Caudy, RF Ketting, SM Hammond, AM Denli… - Nature, 2003 - nature.com
RNA interference (RNAi) regulates gene expression by the cleavage of messenger RNA, by
mRNA degradation and by preventing protein synthesis. These effects are mediated by a …

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives

I Callebaut, G Labesse, P Durand, A Poupon… - Cellular and Molecular …, 1997 - Springer
Ten years after the idea of hydrophobic cluster analysis (HCA) was conceived and first pub
lished, theoretical and practical experience has shown this unconventional method of …

The Proto-Oncogene c-myc Is a Direct Target Gene of Epstein-Barr Virus Nuclear Antigen 2

C Kaiser, G Laux, D Eick, N Jochner… - Journal of …, 1999 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects and transforms primary B lymphocytes in vitro. Viral infection
initiates the cell cycle entry of the resting B lymphocytes. The maintenance of proliferation in …

Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease

SH Low, S Vasanth, CH Larson, S Mukherjee… - Developmental cell, 2006 - cell.com
Primary cilia are implicated in the pathogenesis of autosomal-dominant polycystic kidney
disease (ADPKD), which results from defects in polycystin-1 (PC1), but the function of PC1 …

Readers of histone methylarginine marks

S Gayatri, MT Bedford - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
Arginine methylation is a common posttranslational modification (PTM) that alters roughly
0.5% of all arginine residues in the cells. There are three types of arginine methylation …

Editor meets silencer: crosstalk between RNA editing and RNA interference

K Nishikura - Nature Reviews Molecular Cell Biology, 2006 - nature.com
The most prevalent type of RNA editing is mediated by ADAR (adenosine deaminase acting
on RNA) enzymes, which convert adenosines to inosines (a process known as A→ I RNA …

Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma

BK Yoo, PK Santhekadur, R Gredler, D Chen… - Hepatology, 2011 - journals.lww.com
There is virtually no effective treatment for advanced hepatocellular carcinoma (HCC) and
novel targets need to be identified to develop effective treatment. We recently documented …