Epstein–Barr virus latent genes
MS Kang, E Kieff - Experimental & molecular medicine, 2015 - nature.com
Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …
Metacaspases
L Tsiatsiani, F Van Breusegem, P Gallois… - Cell Death & …, 2011 - nature.com
Metacaspases are cysteine-dependent proteases found in protozoa, fungi and plants and
are distantly related to metazoan caspases. Although metacaspases share structural …
are distantly related to metazoan caspases. Although metacaspases share structural …
[HTML][HTML] A pan-cancer analysis of the oncogenic role of staphylococcal nuclease domain-containing protein 1 (SND1) in human tumors
X Cui, X Zhang, M Liu, C Zhao, N Zhang, Y Ren, C Su… - Genomics, 2020 - Elsevier
Although emerging cell-or animal-based evidence supports the relationship between SND1
and cancers, no pan-cancer analysis is available. We thus first explored the potential …
and cancers, no pan-cancer analysis is available. We thus first explored the potential …
A micrococcal nuclease homologue in RNAi effector complexes
RNA interference (RNAi) regulates gene expression by the cleavage of messenger RNA, by
mRNA degradation and by preventing protein synthesis. These effects are mediated by a …
mRNA degradation and by preventing protein synthesis. These effects are mediated by a …
Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives
Ten years after the idea of hydrophobic cluster analysis (HCA) was conceived and first pub
lished, theoretical and practical experience has shown this unconventional method of …
lished, theoretical and practical experience has shown this unconventional method of …
The Proto-Oncogene c-myc Is a Direct Target Gene of Epstein-Barr Virus Nuclear Antigen 2
C Kaiser, G Laux, D Eick, N Jochner… - Journal of …, 1999 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects and transforms primary B lymphocytes in vitro. Viral infection
initiates the cell cycle entry of the resting B lymphocytes. The maintenance of proliferation in …
initiates the cell cycle entry of the resting B lymphocytes. The maintenance of proliferation in …
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
SH Low, S Vasanth, CH Larson, S Mukherjee… - Developmental cell, 2006 - cell.com
Primary cilia are implicated in the pathogenesis of autosomal-dominant polycystic kidney
disease (ADPKD), which results from defects in polycystin-1 (PC1), but the function of PC1 …
disease (ADPKD), which results from defects in polycystin-1 (PC1), but the function of PC1 …
Readers of histone methylarginine marks
S Gayatri, MT Bedford - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
Arginine methylation is a common posttranslational modification (PTM) that alters roughly
0.5% of all arginine residues in the cells. There are three types of arginine methylation …
0.5% of all arginine residues in the cells. There are three types of arginine methylation …
Editor meets silencer: crosstalk between RNA editing and RNA interference
K Nishikura - Nature Reviews Molecular Cell Biology, 2006 - nature.com
The most prevalent type of RNA editing is mediated by ADAR (adenosine deaminase acting
on RNA) enzymes, which convert adenosines to inosines (a process known as A→ I RNA …
on RNA) enzymes, which convert adenosines to inosines (a process known as A→ I RNA …
Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma
BK Yoo, PK Santhekadur, R Gredler, D Chen… - Hepatology, 2011 - journals.lww.com
There is virtually no effective treatment for advanced hepatocellular carcinoma (HCC) and
novel targets need to be identified to develop effective treatment. We recently documented …
novel targets need to be identified to develop effective treatment. We recently documented …