This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

The survival of patients with cystic fibrosis (CF) continues to improve. The discovery and
cloning of the CFTR gene more than 21 years ago led to the identification of the structure …

Since the last statements on pulmonary rehabilitation by the American Thoracic Society
(ATS; 1999) and the European Respiratory Society (ERS; 1997), there have been numerous …

Conclusion This is the first extensive systematic literature review undertaken of the existing
evidence surrounding comprehensive physiotherapy management of the spontaneously …

A significant increase in life expectancy in successive birth cohorts of people with cystic
fibrosis (CF) is a result of more effective treatment for the disease. It is also now widely …

Background People with non‐cystic fibrosis bronchiectasis commonly experience chronic
cough and sputum production, features that may be associated with progressive decline in …

Cystic fibrosis (CF) is a genetic disease characterized by dehydration of airway surface
liquid and impaired mucociliary clearance. As a result, there is difficulty clearing pathogens …

Background Chest physiotherapy is widely prescribed to assist the clearance of airway
secretions in people with cystic fibrosis (CF). Positive expiratory pressure (PEP) devices …

Physiotherapy management is a key element of care for people with cystic fibrosis (CF)
throughout the lifespan. Although considerable evidence exists to support physiotherapy …

In patients with cystic fibrosis (CF), early intervention and prevention of lung disease is of
paramount importance. Principles to achieve this aim include early diagnosis of CF, regular …