ABSTRACT Introduction Metallo-β-lactamases (MBLs) are enzymes produced by bacteria
that confer resistance to most β-lactam antibiotics, including carbapenems, which have the …

Some antibiotics that are frequently employed are β-lactams. In light of the hydrolytic
process of β-lactamase, found in Gram-negative bacteria, inhibitors of β-lactamase (BLIs) …

The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …

Comprehensive Summary Alkaloids are one of the prominent members in the development
of new antimicrobial agents. This work discovered a class of alkaloid quinazolone‐derived …

Bacterial infections caused by methicillin-resistant Staphylococcus aureus have seriously
threatened public health. There is an urgent need to propose an existing regimen to …

Metallo-β-lactamases (MBLs) are zinc-dependent enzymes capable of hydrolyzing all
bicyclic β-lactam antibiotics, posing a great threat to public health. However, there are …

Bacterial resistance is undoubtedly one of the main public health concerns especially with
the emergence of metallo-β-lactamases (MBLs) able to hydrolytically inactivate β-lactam …

Background/Objectives: Among various carbapenemases, New Delhi metallo-beta-
lactamases (NDMs) are recognized as the most powerful type capable of hydrolyzing all …

A photocatalytic chemodivergent reaction for the selectivity formation of C–S and C–N bonds
in a controlled manner was proposed. The reaction medium, either neutral or acidic, is …

The worldwide emergence and dissemination of Gram-negative bacteria expressing metallo-
β-lactamases (MBLs) menace the efficacy of all β-lactam antibiotics, including carbapenems …