Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

The serotonin system in autism spectrum disorder: From biomarker to animal models

CL Muller, AMJ Anacker, J Veenstra-VanderWeele - Neuroscience, 2016 - Elsevier
Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …

Oxytocin-dependent reopening of a social reward learning critical period with MDMA

R Nardou, EM Lewis, R Rothhaas, R Xu, A Yang… - Nature, 2019 - nature.com
A critical period is a developmental epoch during which the nervous system is expressly
sensitive to specific environmental stimuli that are required for proper circuit organization …

Breaking the loop: oxytocin as a potential treatment for drug addiction

IS McGregor, MT Bowen - Hormones and behavior, 2012 - Elsevier
Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

The prosocial effects of 3, 4-methylenedioxymethamphetamine (MDMA): controlled studies in humans and laboratory animals

P Kamilar-Britt, G Bedi - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Abstract Users of±3, 4-methylenedioxymethamphetamine (MDMA;'ecstasy') report prosocial
effects such as sociability and empathy. Supporting these apparently unique social effects …

[HTML][HTML] The effects of acutely administered 3, 4-methylenedioxymethamphetamine on spontaneous brain function in healthy volunteers measured with arterial spin …

RL Carhart-Harris, K Murphy, R Leech, D Erritzoe… - Biological …, 2015 - Elsevier
Abstract Background The compound 3, 4-methylenedioxymethamphetamine (MDMA) is a
potent monoamine releaser that produces an acute euphoria in most individuals. Methods In …

Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin

F Holze, I Avedisian, N Varghese, A Eckert… - Frontiers in …, 2021 - frontiersin.org
The psychedelic lysergic acid diethylamide (LSD) has experienced a revival in research,
including clinical trials that evaluate LSD-assisted psychotherapy. LSD induces perceptual …

Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3, 4-methylenedioxymethamphetamine (MDMA)

MB Young, SD Norrholm, LM Khoury, T Jovanovic… - …, 2017 - Springer
Abstract Rationale 3, 4-Methylenedioxymethamphetamine (MDMA) persistently improves
symptoms of post-traumatic stress disorder (PTSD) when combined with psychotherapy …

The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants?

AK Bershad, MA Miller, MJ Baggott… - Journal of …, 2016 - journals.sagepub.com
±3, 4-Methylenedioxymethamphetamine (MDMA) is a popular recreational drug that
enhances sociability and feelings of closeness with others. These “prosocial” effects appear …

Acute prosocial effects of oxytocin and vasopressin when given alone or in combination with 3, 4-methylenedioxymethamphetamine in rats: involvement of the V1A …

L Ramos, C Hicks, R Kevin, A Caminer… - …, 2013 - nature.com
The neuropeptides oxytocin (OT) and vasopressin (AVP) are recognized for their modulation
of social processes in humans when delivered peripherally. However, there is surprisingly …