New Insights into the Pathogenesis of Metabolic-Associated Fatty Liver Disease (MAFLD): Gut–Liver–Heart Crosstalk

K Yang, M Song - Nutrients, 2023 - mdpi.com
Metabolism-associated fatty liver disease (MAFLD) is a multifaceted disease that involves
complex interactions between various organs, including the gut and heart. It is defined by …

The effect of bioactive aliment compounds and micronutrients on non-alcoholic fatty liver disease

C Munteanu, B Schwartz - Antioxidants, 2023 - mdpi.com
In the current review, we focused on identifying aliment compounds and micronutrients, as
well as addressed promising bioactive nutrients that may interfere with NAFLD advance and …

Apigenin alleviated high-fat-diet-induced hepatic pyroptosis by mitophagy-ROS-CTSB-NLRP3 pathway in mice and AML12 cells

Z Meng, M Gao, C Wang, S Guan… - Journal of Agricultural …, 2023 - ACS Publications
Apigenin is considered the most-known natural flavonoid and is abundant in a wide variety
of fruits and vegetables. A high fat diet (HFD) can induce liver injury and hepatocyte death in …

Novel potential therapeutic targets of alopecia areata

W Xu, S Wan, B Xie, X Song - Frontiers in Immunology, 2023 - frontiersin.org
Alopecia areata (AA) is a non-scarring hair loss disorder caused by autoimmunity. The
immune collapse of the hair follicle, where interferon-gamma (IFN-γ) and CD8+ T cells …

Interplay of lymphocytes with the intestinal microbiota in children with nonalcoholic fatty liver disease

T Liang, D Li, J Zunong, M Li, N Amaerjiang, H Xiao… - Nutrients, 2022 - mdpi.com
Abnormally high lymphocyte counts are seen in persons with nonalcoholic fatty liver disease
(NAFLD). Gut microbiota dysbiosis is a risk factor for NAFLD. We assessed the gut …

Topical rhubarb charcoal-crosslinked chitosan/silk fibroin sponge scaffold for the repair of diabetic ulcers improves hepatic lipid deposition in db/db mice via the AMPK …

Q Tan, Q He, Z Peng, X Zeng, Y Liu, D Li… - Lipids in Health and …, 2024 - Springer
Background Type 2 diabetes mellitus (T2DM) is closely linked to metabolic syndrome,
characterised by insulin resistance, hyperglycaemia, abnormal lipid metabolism, and …

Immunomodulation in non-alcoholic fatty liver disease: exploring mechanisms and applications

Z Guo, Q Wu, P Xie, J Wang, W Lv - Frontiers in Immunology, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) exhibits increased lipid enrichment in
hepatocytes. The spectrum of this disease includes stages such as nonalcoholic simple fatty …

Risk of infections in non‐alcoholic fatty liver disease: A nationwide population‐based cohort study

Y Shang, L Widman, F Ebrahimi… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Previous literature suggests an association between non‐
alcoholic fatty liver disease (NAFLD) and infections. We aimed to determine the rate and risk …

Calenduloside E ameliorates non-alcoholic fatty liver disease via modulating a pyroptosis-dependent pathway.

Y Le, J Guo, Z Liu, J Liu, Y Liu, H Chen, J Qiu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Non-alcoholic fatty liver disease (NAFLD) is a prevalent
chronic liver condition that can have multiple underlying causes. There are no satisfactory …

Differential peripheral memory T cell subsets sensitively indicate the severity of nonalcoholic fatty liver disease

A Kado, T Tsutsumi, H Yotsuyanagi… - Hepatology …, 2024 - Wiley Online Library
Aim Differential patterns of peripheral memory T cell subsets in nonalcoholic fatty liver
disease (NAFLD) were assessed using flow cytometry (FCM) to elucidate their association …