The challenge of the proteome dynamic range and its implications for in‐depth proteomics
RA Zubarev - Proteomics, 2013 - Wiley Online Library
The dynamic range of the cellular proteome approaches seven orders of magnitude—from
one copy per cell to ten million copies per cell. Since a proteome's abundance distribution …
one copy per cell to ten million copies per cell. Since a proteome's abundance distribution …
Microbial metaproteomics for characterizing the range of metabolic functions and activities of human gut microbiota
W Xiong, PE Abraham, Z Li, C Pan, RL Hettich - Proteomics, 2015 - Wiley Online Library
The human gastrointestinal tract is a complex, dynamic ecosystem that consists of a carefully
tuned balance of human host and microbiota membership. The microbiome is not merely a …
tuned balance of human host and microbiota membership. The microbiome is not merely a …
Systematic comparison of label-free, metabolic labeling, and isobaric chemical labeling for quantitative proteomics on LTQ Orbitrap Velos
Z Li, RM Adams, K Chourey, GB Hurst… - Journal of proteome …, 2012 - ACS Publications
A variety of quantitative proteomics methods have been developed, including label-free,
metabolic labeling, and isobaric chemical labeling using iTRAQ or TMT. Here, these …
metabolic labeling, and isobaric chemical labeling using iTRAQ or TMT. Here, these …
Transcript, protein and metabolite temporal dynamics in the CAM plant Agave
PE Abraham, H Yin, AM Borland, D Weighill, SD Lim… - Nature Plants, 2016 - nature.com
Already a proven mechanism for drought resilience, crassulacean acid metabolism (CAM) is
a specialized type of photosynthesis that maximizes water-use efficiency by means of an …
a specialized type of photosynthesis that maximizes water-use efficiency by means of an …
Nutrients drive transcriptional changes that maintain metabolic homeostasis but alter genome architecture in Microcystis
MM Steffen, SP Dearth, BD Dill, Z Li… - The ISME …, 2014 - academic.oup.com
The cyanobacterium Microcystis aeruginosa is a globally distributed bloom-forming
organism that degrades freshwater systems around the world. Factors that drive its …
organism that degrades freshwater systems around the world. Factors that drive its …
[HTML][HTML] Genome-resolved metaproteomic characterization of preterm infant gut microbiota development reveals species-specific metabolic shifts and variabilities …
W Xiong, CT Brown, MJ Morowitz, JF Banfield… - Microbiome, 2017 - Springer
Background Establishment of the human gut microbiota begins at birth. This early-life
microbiota development can impact host physiology during infancy and even across an …
microbiota development can impact host physiology during infancy and even across an …
[HTML][HTML] Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn's remission patients despite …
JA Blakeley-Ruiz, AR Erickson, BL Cantarel, W Xiong… - Microbiome, 2019 - Springer
Background The gut microbiome plays a fundamental role in the human host's overall health
by contributing key biological functions such as expanded metabolism and pathogen …
by contributing key biological functions such as expanded metabolism and pathogen …
Transcription factor-mediated cell-to-cell signalling in plants
X Han, D Kumar, H Chen, S Wu… - Journal of experimental …, 2014 - academic.oup.com
Plant cells utilize mobile transcription factors to transmit intercellular signals when they
perceive environmental stimuli or initiate developmental programmes. Studies on these …
perceive environmental stimuli or initiate developmental programmes. Studies on these …
Development of an enhanced metaproteomic approach for deepening the microbiome characterization of the human infant gut
W Xiong, RJ Giannone, MJ Morowitz… - Journal of proteome …, 2015 - ACS Publications
The establishment of early life microbiota in the human infant gut is highly variable and plays
a crucial role in host nutrient availability/uptake and maturation of immunity. Although high …
a crucial role in host nutrient availability/uptake and maturation of immunity. Although high …
Metaproteomics reveals functional shifts in microbial and human proteins during a preterm infant gut colonization case
JC Young, C Pan, RM Adams, B Brooks… - …, 2015 - Wiley Online Library
Microbial colonization of the human gastrointestinal tract plays an important role in
establishing health and homeostasis. However, the time‐dependent functional signatures of …
establishing health and homeostasis. However, the time‐dependent functional signatures of …