Parameterized algorithms in bioinformatics: an overview

L Bulteau, M Weller - Algorithms, 2019 - mdpi.com
Bioinformatics regularly poses new challenges to algorithm engineers and theoretical
computer scientists. This work surveys recent developments of parameterized algorithms …

Quantifying MCMC exploration of phylogenetic tree space

C Whidden, FA Matsen IV - Systematic biology, 2015 - academic.oup.com
In order to gain an understanding of the effectiveness of phylogenetic Markov chain Monte
Carlo (MCMC), it is important to understand how quickly the empirical distribution of the …

Reassortment between influenza B lineages and the emergence of a coadapted PB1–PB2–HA gene complex

G Dudas, T Bedford, S Lycett… - Molecular biology and …, 2015 - academic.oup.com
Influenza B viruses make a considerable contribution to morbidity attributed to seasonal
influenza. Currently circulating influenza B isolates are known to belong to two antigenically …

A metric for phylogenetic trees based on matching

Y Lin, V Rajan, BME Moret - IEEE/ACM Transactions on …, 2011 - ieeexplore.ieee.org
Comparing two or more phylogenetic trees is a fundamental task in computational biology.
The simplest outcome of such a comparison is a pairwise measure of similarity, dissimilarity …

An algorithm for constructing parsimonious hybridization networks with multiple phylogenetic trees

Y Wu - Journal of Computational Biology, 2013 - liebertpub.com
A phylogenetic network is a model for reticulate evolution. A hybridization network is one
type of phylogenetic network for a set of discordant gene trees and “displays” each gene …

Supertrees based on the subtree prune-and-regraft distance

C Whidden, N Zeh, RG Beiko - Systematic biology, 2014 - academic.oup.com
Supertree methods reconcile a set of phylogenetic trees into a single structure that is often
interpreted as a branching history of species. A key challenge is combining conflicting …

Fixed-parameter algorithms for maximum agreement forests

C Whidden, RG Beiko, N Zeh - SIAM Journal on Computing, 2013 - SIAM
We present new and improved fixed-parameter algorithms for computing maximum
agreement forests of pairs of rooted binary phylogenetic trees. The size of such a forest for …

Fast computation of minimum hybridization networks

B Albrecht, C Scornavacca, A Cenci, DH Huson - Bioinformatics, 2012 - academic.oup.com
Motivation: Hybridization events in evolution may lead to incongruent gene trees. One
approach to determining possible interspecific hybridization events is to compute a …

Fast FPT algorithms for computing rooted agreement forests: theory and experiments

C Whidden, RG Beiko, N Zeh - … , SEA 2010, Ischia Island, Naples, Italy …, 2010 - Springer
We improve on earlier FPT algorithms for computing a rooted maximum agreement forest
(MAF) or a maximum acyclic agreement forest (MAAF) of a pair of phylogenetic trees. Their …

On unrooted and root-uncertain variants of several well-known phylogenetic network problems

L Van Iersel, S Kelk, G Stamoulis, L Stougie, O Boes - Algorithmica, 2018 - Springer
The hybridization number problem requires us to embed a set of binary rooted phylogenetic
trees into a binary rooted phylogenetic network such that the number of nodes with indegree …