The microbiome has received increasing attention over the last 15 years. Although gut
microbes have been explored for several decades, investigations of the role of …

Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Irritable bowel syndrome (IBS), one of the most frequent digestive disorders, is characterized
by chronic and recurrent abdominal pain and altered bowel habit. The origin seems to be …

Objectives Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic cysts that can
progress to invasive pancreatic cancer. Associations between oncogenesis and oral …

Proton pump inhibitors (PPIs) reliably suppress gastric acid secretion and are therefore the
first‐line treatment for gastric acid‐related disorders. Hypomagnesemia (serum magnesium …

Background & Aims Proton pump inhibitors (PPIs) have a major impact on gut microbiome
and immune function, which in turn, may increase the risk of inflammatory bowel disease …

Conclusions TNIP3 is a regulator of hepatic I/R injury that alleviates cell death and
inflammation by assisting ubiquitination and degradation of LATS2 and the resultant YAP …

Gastric juice is a unique combination of hydrochloric acid (HCl), lipase, and pepsin. Acidic
gastric juice is found in all vertebrates, and its main function is to inactivate microorganisms …

Airborne microorganisms in the upper troposphere and lower stratosphere remain elusive
due to a lack of reliable sample collection systems. To address this problem, we designed …

Background Proton pump inhibitors (PPI) are widely used to treat acid‐related disorders of
the upper gastrointestinal tract. However, large observational studies have raised concerns …