Interactions between hyaluronan and its receptors (CD44, RHAMM) regulate the activities of inflammation and cancer

S Misra, VC Hascall, RR Markwald… - Frontiers in …, 2015 - frontiersin.org
The glycosaminoglycan hyaluronan (HA), a major component of extracellular matrices, and
cell surface receptors of HA have been proposed to have pivotal roles in cell proliferation …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016 - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

Hydrogel scaffolds for differentiation of adipose-derived stem cells

Q Huang, Y Zou, MC Arno, S Chen, T Wang… - Chemical Society …, 2017 - pubs.rsc.org
Natural extracellular matrices (ECMs) have been widely used as a support for the adhesion,
migration, differentiation, and proliferation of adipose-derived stem cells (ADSCs). However …

Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering

Y Jiang, J Chen, C Deng, EJ Suuronen, Z Zhong - Biomaterials, 2014 - Elsevier
Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for
sustained protein release, targeted drug delivery, and tissue engineering due to excellent …

Bacterial Hyaluronidase Self-Triggered Prodrug Release for Chemo-Photothermal Synergistic Treatment of Bacterial Infection.

H Ji, K Dong, Z Yan, C Ding, Z Chen… - Small (Weinheim an …, 2016 - europepmc.org
A novel platform for targeted on-demand prodrug ascorbic acid (AA) delivery is fabricated
using a bacterial hyaluronidase sensitive graphene-mesoporous silica nanosheet …

Inherent anchorages in UiO-66 nanoparticles for efficient capture of alendronate and its mediated release

X Zhu, J Gu, Y Wang, B Li, Y Li, W Zhao… - Chemical …, 2014 - pubs.rsc.org
Zr-based MOF nanoparticles were applied as efficient carriers for alendronate delivery, and
an unprecedented drug loading capacity was achieved thanks to the inherent drug …

[HTML][HTML] Bisphosphonate conjugation for bone specific drug targeting

KB Farrell, A Karpeisky, DH Thamm, S Zinnen - Bone reports, 2018 - Elsevier
Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …

Polylactide (PLA)-based amphiphilic block copolymers: synthesis, self-assembly, and biomedical applications

JK Oh - Soft Matter, 2011 - pubs.rsc.org
Polylactide (PLA) and its copolymers are one type of hydrophobic aliphatic polyester based
on hydroxyalkanoic acids. They possess exceptional qualities: biocompatibility; FDA …

Fabrication of novel MXene (Ti 3 C 2)/polyacrylamide nanocomposite hydrogels with enhanced mechanical and drug release properties

P Zhang, XJ Yang, P Li, Y Zhao, QJ Niu - Soft Matter, 2020 - pubs.rsc.org
A highly stretchable nanocomposite (NC) hydrogel was fabricated via in situ free radical
polymerization of acrylamide. In particular, an exfoliated two-dimensional MXene (Ti3C2) …

Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering

J Dahlmann, A Krause, L Möller, G Kensah, M Möwes… - Biomaterials, 2013 - Elsevier
Despite recent major advances including reprogramming and directed cardiac differentiation
of human cells, therapeutic application of in vitro engineered myocardial tissue is still not …