Urokinase-type plasminogen activator receptor (uPAR) expression is elevated during
inflammation and tissue remodelling and in many human cancers, in which it frequently …

soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and
elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in …

Zinc is an essential trace element required for enzymatic activity and for maintaining the
conformation of many transcription factors; thus, zinc homeostasis is tightly regulated …

The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LpL) along the
luminal surface of the capillaries. However, the endothelial cell molecule that facilitates …

Plasma membrane urokinase-type plasminogen activator (uPA)-receptor (uPAR) is a GPI-
anchored protein that binds with high-affinity and activates the serine protease uPA, thus …

P2Y12, a G protein-coupled receptor that plays a central role in platelet activation has been
recently identified as the receptor targeted by the antithrombotic drug, clopidogrel. In this …

Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-
inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease …

The urokinase-type plasminogen activator (uPA), its inhibitor PA I-1 and its cellular receptor
(uPAR), play a pivotal role in pericellular proteolysis. In addition, through their interactions …

Expression of the membrane receptor uPAR induces profound changes in cell morphology
and migration, and its expression correlates with the malignant phenotype of cancers. To …

An essential but insufficient step for apical sorting of glycosylphosphatidylinositol (GPI)-
anchored proteins (GPI-APs) in epithelial cells is their association with detergent-resistant …