Ribosomes are macromolecular machines that are globally required for the translation of all
proteins in all cells. Ribosome biogenesis, which is essential for cell growth, proliferation …

The intrinsic cellular heterogeneity and molecular complexity of the mammalian nervous
system relies substantially on the dynamic nature and spatiotemporal patterning of gene …

With few exceptions, the marked advances in knowledge about the genetic basis of
schizophrenia have not converged on findings that can be confidently used for precise …

Epithelial-mesenchymal transition (EMT) is reported to involve in the crosstalk between
tumor cells and tumor-associated macrophages (TAMs). Exosomes are considered as …

Background Tumor microenvironment (TME) is a complex environment containing tumor
cells, tumor-associated macrophages (TAMs), interstitial cells, and non-cellular components …

The elucidation of gene regulatory networks is one of the major challenges of systems
biology. Measurements about genes that are exploited by network inference methods are …

Epitranscriptomic modifications can impact behavior. Here, we used Drosophila
melanogaster to study N6-methyladenosine (m6A), the most abundant modification of …

To understand the functional roles of RNA in the cell, it is essential to elucidate the dynamics
of their production, processing and decay. A recent method for assessing mRNA dynamics is …

Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms
involved are not fully understood. We found that zygotic mRNA stability in Drosophila …

Regulation of mRNA degradation is critical for a diverse array of cellular processes and
developmental cell fate decisions. Many methods for determining mRNA half-lives rely on …