Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational research

MR Grovola, C von Reyn, DJ Loane… - Journal of …, 2023 - Springer
Traumatic brain injury (TBI) often results in prolonged or permanent brain dysfunction with
over 2.8 million affected annually in the US, including over 56,000 deaths, with over 5 million …

Backpack-mediated anti-inflammatory macrophage cell therapy for the treatment of traumatic brain injury

N Kapate, R Liao, RL Sodemann, T Stinson… - PNAS …, 2024 - academic.oup.com
Traumatic brain injury (TBI) is a debilitating disease with no current therapies outside of
acute clinical management. While acute, controlled inflammation is important for debris …

Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditions

X Wu, Y Ni, W Li, B Yang, X Yang, Z Zhu… - Journal of Biological …, 2024 - ASBMB
A renewable source of porcine macrophages derived from pluripotent stem cells (PSCs)
would be a valuable alternative to primary porcine alveolar macrophages (PAMs) in the …