[HTML][HTML] Lipopolysaccharide recognition in the crossroads of TLR4 and caspase-4/11 mediated inflammatory pathways
A Zamyatina, H Heine - Frontiers in Immunology, 2020 - frontiersin.org
The innate immune response to lipopolysaccharide is essential for host defense against
Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is …
Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is …
[HTML][HTML] Enteropathogenic Escherichia coli—A Summary of the Literature
Diarrheal disease is still a major public health concern, as it is still considered an important
cause of death in children under five years of age. A few decades ago, the detection of …
cause of death in children under five years of age. A few decades ago, the detection of …
Host‐microbe interaction in the gastrointestinal tract
A Parker, MAE Lawson, L Vaux… - Environmental …, 2018 - Wiley Online Library
The gastrointestinal tract is a highly complex organ in which multiple dynamic physiological
processes are tightly coordinated while interacting with a dense and extremely diverse …
processes are tightly coordinated while interacting with a dense and extremely diverse …
Mechanisms and consequences of noncanonical inflammasome-mediated pyroptosis
SS Wright, SO Vasudevan, VA Rathinam - Journal of molecular biology, 2022 - Elsevier
The noncanonical inflammasome, comprising inflammatory caspases 4, 5, or 11, monitors
the cytosol for bacterial lipopolysaccharide (LPS). Intracellular LPS-elicited autoproteolysis …
the cytosol for bacterial lipopolysaccharide (LPS). Intracellular LPS-elicited autoproteolysis …
Host inflammasome defense mechanisms and bacterial pathogen evasion strategies
SM Brewer, SW Brubaker, DM Monack - Current opinion in immunology, 2019 - Elsevier
Highlights•The innate immune system utilizes a set of multiprotein complexes called
inflammasomes that can be triggered during infection.•Inflammasome activation supports …
inflammasomes that can be triggered during infection.•Inflammasome activation supports …
Modulation of host cell processes by T3SS effectors
AR Shenoy, RCD Furniss, PJ Goddard… - Escherichia coli, a …, 2018 - Springer
Two of the enteric Escherichia coli pathotypes—enteropathogenic E. coli (EPEC) and
enterohaemorrhagic E. coli (EHEC)—have a conserved type 3 secretion system which is …
enterohaemorrhagic E. coli (EHEC)—have a conserved type 3 secretion system which is …
Molecular mechanisms employed by enteric bacterial pathogens to antagonise host innate immunity
J Gan, C Giogha, EL Hartland - Current opinion in microbiology, 2021 - Elsevier
Highlights•Enteric bacterial pathogens utilise secreted effector proteins to inhibit host
inflammatory and cell death signaling.•Many effector proteins are enzymes that target …
inflammatory and cell death signaling.•Many effector proteins are enzymes that target …
病原体逃逸宿主固有免疫的新策略: 抑制细胞焦亡
杨茂艺， 崔潇月， 郑诗棋， 马诗瑶， 郑增长， 邓万燕 - 遗传, 2023 - chinagene.cn
细胞焦亡是一种由Gasdermin 家族蛋白介导的新型程序性细胞死亡. 当宿主细胞感应病原体
感染或其他危险信号时, Gasdermin 家族蛋白被切割活化并诱导细胞焦亡 …
感染或其他危险信号时, Gasdermin 家族蛋白被切割活化并诱导细胞焦亡 …
Virulence-related O islands in enterohemorrhagic Escherichia coli O157: H7
L Jiang, W Yang, X Jiang, T Yao, L Wang, B Yang - Gut microbes, 2021 - Taylor & Francis
ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) O157: H7 is a principally
foodborne pathogen linked to serious diseases, including bloody diarrhea, hemorrhagic …
foodborne pathogen linked to serious diseases, including bloody diarrhea, hemorrhagic …
Unraveling enterohemorrhagic Escherichia coli infection: the promising role of dietary compounds and probiotics in bacterial elimination and host innate immunity …
The innate immune system has developed sophisticated strategies to defense against
infections. Host cells utilize the recognition machineries such as toll-like receptors and …
infections. Host cells utilize the recognition machineries such as toll-like receptors and …