DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells

K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018 - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

Building membrane nanopores

S Howorka - Nature nanotechnology, 2017 - nature.com
Membrane nanopores—hollow nanoscale barrels that puncture biological or synthetic
membranes—have become powerful tools in chemical-and biosensing, and have achieved …

An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2

W Ma, Y Zhan, Y Zhang, X Shao, X Xie, C Mao… - Nano …, 2019 - ACS Publications
DNA nanorobots have emerged as new tools for nanomedicine with the potential to
ameliorate the delivery and anticancer efficacy of various drugs. DNA nanostructures have …

A reversibly gated protein-transporting membrane channel made of DNA

S Dey, A Dorey, L Abraham, Y Xing, I Zhang… - Nature …, 2022 - nature.com
Controlled transport of biomolecules across lipid bilayer membranes is of profound
significance in biological processes. In cells, cargo exchange is mediated by dedicated …

A large size-selective DNA nanopore with sensing applications

RP Thomsen, MG Malle, AH Okholm, S Krishnan… - Nature …, 2019 - nature.com
Transmembrane nanostructures like ion channels and transporters perform key biological
functions by controlling flow of molecules across lipid bilayers. Much work has gone into …

New tricks for old dogs: improving the accuracy of biomolecular force fields by pair-specific corrections to non-bonded interactions

J Yoo, A Aksimentiev - Physical Chemistry Chemical Physics, 2018 - pubs.rsc.org
In contrast to ordinary polymers, the vast majority of biological macromolecules adopt highly
ordered three-dimensional structures that define their functions. The key to folding of a …