The placenta is crucial for fetal development, yet the impact of environmental stressors such
as arsenic exposure remains poorly understood. We apply single-cell RNA sequencing to …

The human endometrial decidualization is a transformative event in the pregnant uterus that
involves the differentiation of stromal cells into decidual cells. While crucial to the …

The role of the chorio-allantoic placenta as the critical nutrient-and oxygen-supplying organ
to nourish the demands of the fetus has been well recognized. This function relies on the …

The placenta becomes one of the most diversified organs during placental mammal
radiation. The main in vitro model for studying mouse trophoblast development is the 2D …

Leucine-rich repeat-containing G protein-coupled receptors 5/4 (LGR5/LGR4) are critical
stem cell markers in epithelial tissues including intestine. They agonise wingless-related …

The placenta is the critical interface between mother and fetus, and consequently, placental
dysfunction underlies many pregnancy complications. Placental formation requires an …

The contribution of placental immune responses to congenital Zika virus (ZIKV) syndrome
remains poorly understood. Here, we leveraged a mouse model of ZIKV infection to identify …

The placenta is essential organ for oxygen and nutrient exchange between the mother and
the developing fetus. Trophoblast lineage differentiation is closely related to the normal …

Pregnant women are often prescribed or abuse opioid drugs. The placenta is likely the key
to understanding how opioids cause adverse pregnancy outcomes. Maternal oxycodone …

The placenta establishes a maternal–fetal exchange interface to transport nutrients and
gases between the mother and the fetus. Establishment of this exchange interface relies on …