Hepatitis C virus hijacks host lipid metabolism

GH Syed, Y Amako, A Siddiqui - Trends in Endocrinology & Metabolism, 2010 - cell.com
Hepatitis C virus (HCV) enhances its replication by modulating host cell lipid metabolism.
HCV circulates in the blood in association with lipoproteins. HCV infection is associated with …

Hepatitis C virus cell entry: role of lipoproteins and cellular receptors

ME Burlone, A Budkowska - Journal of General Virology, 2009 - microbiologyresearch.org
Hepatitis C virus (HCV), a major cause of chronic liver disease, is a single-stranded positive
sense virus of the family Flaviviridae. HCV cell entry is a multi-step process, involving …

Hepatitis C virus, cholesterol and lipoproteins—impact for the viral life cycle and pathogenesis of liver disease

DJ Felmlee, ML Hafirassou, M Lefevre, TF Baumert… - Viruses, 2013 - mdpi.com
Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic
hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates …

Extrahepatic disease manifestations of HCV infection: some current issues

V Agnello, FG De Rosa - Journal of hepatology, 2004 - Elsevier
Productive hepatitis C virus (HCV) infection appears to be primarily, and in most patients
almost exclusively, confined to the liver. However, a wide variety of extrahepatic disease …

Hepatitis C virus particles and lipoprotein metabolism

P André, G Perlemuter, A Budkowska… - Seminars in liver …, 2005 - thieme-connect.com
The majority of infectious hepatitis C particles are present in the low-density fractions from
plasma of infected patients, suggesting an association of the virus with lipoproteins and the …

Cirrhosis in hepatitis C virus-infected patients can be excluded using an index of standard biochemical serum markers

S Islam, L Antonsson, J Westin… - Scandinavian journal of …, 2005 - Taylor & Francis
Objective Assessment of liver histology is pivotal in prognostication and decision-making
regarding therapeutic intervention in patients with chronic hepatitis C virus (HCV). Being an …

Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis

S Mirandola, S Realdon, J Iqbal, M Gerotto, F Dal Pero… - Gastroenterology, 2006 - Elsevier
Background & Aims: Hepatic steatosis is frequent in chronic hepatitis C. Several
mechanisms might be implicated, including metabolic cofactors and direct viral effects on …

Genetic determinants of hepatic steatosis in man

AJ Hooper, LA Adams, JR Burnett - Journal of lipid research, 2011 - ASBMB
Hepatic steatosis is one of the most common liver disorders in the general population. The
main cause of hepatic steatosis is nonalcoholic fatty liver disease (NAFLD), representing the …

[HTML][HTML] HCV genome and life cycle

S Chevaliez, JM Pawlotsky - Hepatitis C viruses: genomes and …, 2006 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection afflicts more than 170 million people worldwide, with the
great majority of patients with acute hepatitis C developing chronic HCV infection. It can …

[PDF][PDF] Fibrosis in genotype 3 chronic hepatitis C and nonalcoholic fatty liver disease: role of insulin resistance and hepatic steatosis

E Bugianesi, G Marchesini, E Gentilcore, IHY Cua… - …, 2006 - Wiley Online Library
Hepatic steatosis has been associated with fibrosis, but it is unknown whether the latter is
independent of the etiology of fat infiltration. We analyzed the relationship between clinical …