Origins of modern human ancestry

A Bergström, C Stringer, M Hajdinjak, EML Scerri… - Nature, 2021 - nature.com
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

[HTML][HTML] Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

AA Pollen, U Kilik, CB Lowe, JG Camp - Nature Reviews Genetics, 2023 - nature.com
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

Modern human incursion into Neanderthal territories 54,000 years ago at Mandrin, France

L Slimak, C Zanolli, T Higham, M Frouin… - Science …, 2022 - science.org
Determining the extent of overlap between modern humans and other hominins in Eurasia,
such as Neanderthals and Denisovans, is fundamental to understanding the nature of their …

[HTML][HTML] The major genetic risk factor for severe COVID-19 is inherited from Neanderthals

H Zeberg, S Pääbo - Nature, 2020 - nature.com
A recent genetic association study identified a gene cluster on chromosome 3 as a risk locus
for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

M Hajdinjak, F Mafessoni, L Skov, B Vernot, A Hübner… - Nature, 2021 - nature.com
Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

Identification of common genetic risk variants for autism spectrum disorder

J Grove, S Ripke, TD Als, M Mattheisen, RK Walters… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

Insights into human genetic variation and population history from 929 diverse genomes

A Bergström, SA McCarthy, R Hui, MA Almarri, Q Ayub… - Science, 2020 - science.org
INTRODUCTION Large-scale human genome-sequencing studies to date have been limited
to large, metropolitan populations or to small numbers of genomes from each group. Much …

[HTML][HTML] The GenomeAsia 100K Project enables genetic discoveries across Asia

Nature, 2019 - nature.com
The underrepresentation of non-Europeans in human genetic studies so far has limited the
diversity of individuals in genomic datasets and led to reduced medical relevance for a large …

The genome of the offspring of a Neanderthal mother and a Denisovan father

V Slon, F Mafessoni, B Vernot, C De Filippo, S Grote… - Nature, 2018 - nature.com
Neanderthals and Denisovans are extinct groups of hominins that separated from each
other more than 390,000 years ago,. Here we present the genome of 'Denisova 11', a bone …

[HTML][HTML] A global meta-analysis of yield stability in organic and conservation agriculture

S Knapp, MGA van der Heijden - Nature communications, 2018 - nature.com
One of the primary challenges of our time is to enhance global food production and security.
Most assessments in agricultural systems focus on plant yield. Yet, these analyses neglect …