[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Functional imaging of the lungs with gas agents

SJ Kruger, SK Nagle, MJ Couch, Y Ohno… - Journal of Magnetic …, 2016 - Wiley Online Library
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Damaged lung gas exchange function of discharged COVID-19 patients detected by hyperpolarized 129Xe MRI

H Li, X Zhao, Y Wang, X Lou, S Chen, H Deng… - Science …, 2021 - science.org
The recovery process of COVID-19 patients is unclear. Some recovered patients complain of
continued shortness of breath. Vasculopathy has been reported in COVID-19, stressing the …

Single‐breath clinical imaging of hyperpolarized 129xe in the airspaces, barrier, and red blood cells using an interleaved 3D radial 1‐point Dixon acquisition

SS Kaushik, SH Robertson… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose We sought to develop and test a clinically feasible 1‐point Dixon, three‐
dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of 129Xe in …

Childhood to adulthood: Accounting for age dependence in healthy‐reference distributions in 129Xe gas‐exchange MRI

JW Plummer, MM Willmering… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose Xenon‐129 (129Xe) gas‐exchange MRI is a pulmonary‐imaging technique that
provides quantitative metrics for lung structure and function and is often compared to …

Quantitative analysis of hyperpolarized 129Xe gas transfer MRI

Z Wang, SH Robertson, J Wang, M He… - Medical …, 2017 - Wiley Online Library
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

Using hyperpolarized 129Xe MRI to quantify the pulmonary ventilation distribution

M He, B Driehuys, LG Que, YCT Huang - Academic radiology, 2016 - Elsevier
Rationale and Objectives Ventilation heterogeneity is impossible to detect with spirometry.
Alternatively, pulmonary ventilation can be imaged three-dimensionally using inhaled 129 …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022 - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

Convolutional neural networks with template-based data augmentation for functional lung image quantification

NJ Tustison, BB Avants, Z Lin, X Feng, N Cullen… - Academic radiology, 2019 - Elsevier
Rationale and Objectives We propose an automated segmentation pipeline based on deep
learning for proton lung MRI segmentation and ventilation-based quantification which …

Comparison of functional free-breathing pulmonary 1H and hyperpolarized 129Xe magnetic resonance imaging in pediatric cystic fibrosis

MJ Couch, S Munidasa, JH Rayment… - Academic radiology, 2021 - Elsevier
Rationale and Objectives Phase resolved functional lung (PREFUL) magnetic resonance
imaging (MRI) is a free-breathing 1 H-based technique that produces maps of fractional …