Diffuse large B cell lymphoma (DLBCL) is a highly heterogeneous lymphoid neoplasm with
variations in gene expression profiles and genetic alterations, which lead to substantial …

Cancer cell metabolism including aerobic glycolysis, amino acid and fatty acid metabolism,
has been extensively studied. Metabolic reprogramming is a major hallmark of cancer …

Axicabtagene ciloleucel (axi-cel) is an anti-CD19 chimeric antigen receptor (CAR) T cell
therapy approved for relapsed/refractory large B cell lymphoma (LBCL) and has treatment …

In diffuse large B cell lymphoma (DLBCL), tumors belonging to the ABC but not GCB gene
expression subgroup rely upon chronic active B cell receptor signaling for viability, a …

DLBCL is the most common lymphoma with high tumor heterogeneity. Treatment
refractoriness and relapse from R-CHOP therapy in patients remain a clinical problem …

The sweetpotato whitefly Bemisia tabaci is a highly destructive agricultural and ornamental
crop pest. It damages host plants through both phloem feeding and vectoring plant …

Members of the VPS13 family are associated with various human diseases. In particular, the
loss of function of VPS13A leads to chorea-acanthocytosis (ChAc), a rare …

Aberrant skipping of coding exons in CD19 and CD22 compromises the response to
immunotherapy in B-cell malignancies. Here, we showed that the MS4A1 gene encoding …

The PR/SET domain family (PRDM) comprise a family of genes whose protein products
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …

Circular RNAs (circRNAs) are a novel class of powerful regulators in gene expression and
participate in the pathogenesis of many diseases, including cancer. However, little is known …