Prosthetic joint infection

AJ Tande, R Patel - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the
global health care industry. While a small minority of joint arthroplasties will become …

Synovial fluid biomarkers for the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis

YS Lee, KH Koo, HJ Kim, S Tian, TY Kim… - JBJS, 2017 - journals.lww.com
Background: The search for a single standard reference test for determining periprosthetic
joint infection (PJI) through analysis of synovial fluid has yielded numerous biomarkers as …

Diagnosis of periprosthetic joint infection: the potential of next-generation sequencing

M Tarabichi, N Shohat, K Goswami, A Alvand… - Jbjs, 2018 - journals.lww.com
Background: Next-generation sequencing is a well-established technique for sequencing of
DNA and has recently gained attention in many fields of medicine. Our aim was to evaluate …

Infection associated with prosthetic joints

JL Del Pozo, R Patel - New England Journal of Medicine, 2009 - Mass Medical Soc
A 62-year-old woman with osteoarthritis presents with a 7-month history of progressively
worsening left hip pain radiating to the groin, 8 months after undergoing total left-hip …

[HTML][HTML] Consensus document for the diagnosis of prosthetic joint infections: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)

A Signore, LM Sconfienza, O Borens… - European journal of …, 2019 - Springer
Background For the diagnosis of prosthetic joint infection, real evidence-based guidelines to
aid clinicians in choosing the most accurate diagnostic strategy are lacking. Aim and …

Diagnosis of periprosthetic joint infection

B Zmistowski, C Della Valle, TW Bauer… - The Journal of …, 2014 - arthroplastyjournal.org
Consensus: Clinically, PJI may be present without meeting these criteria, specifically in the
case of less virulent organisms (eg Propionibacterium acnes). Synovial leukocyte esterase …

Improved diagnosis of periprosthetic joint infection by multiplex PCR of sonication fluid from removed implants

Y Achermann, M Vogt, M Leunig, J Wüst… - Journal of clinical …, 2010 - Am Soc Microbiol
The microbiological diagnosis of periprosthetic joint infection (PJI) is crucial for successful
antimicrobial treatment. Cultures have limited sensitivity, especially in patients receiving …

[HTML][HTML] The alpha-defensin test for periprosthetic joint infection responds to a wide spectrum of organisms

C Deirmengian, K Kardos, P Kilmartin, S Gulati… - … and Related Research®, 2015 - Springer
Background The alpha-defensin test has been previously demonstrated to be highly
accurate in the diagnosis of prosthetic joint infection (PJI), nearly matching the …

Culture-negative periprosthetic joint infection

J Parvizi, OF Erkocak, CJ Della Valle - JBJS, 2014 - journals.lww.com
Culture-Negative Periprosthetic Joint Infection : JBJS Culture-Negative Periprosthetic Joint
Infection : JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques Open …

Multiplex PCR of sonication fluid accurately differentiates between prosthetic joint infection and aseptic failure

ME Portillo, M Salvadó, L Sorli, A Alier, S Martínez… - Journal of Infection, 2012 - Elsevier
OBJECTIVE: Cultures have limited sensitivity in the diagnosis of prosthetic joint infection
(PJI), especially in low-grade infections. We assessed the value of multiplex PCR in …