Doxorubicin is utilized for anti-neoplastic treatment for several decades. The utility of this
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …

Anthracyclines, such as doxorubicin, represent one group of chemotherapy drugs with the
most cardiotoxicity. Despite that anthracyclines are capable of treating assorted solid tumors …

Cardiotoxic side-effects represent a serious complication of anticancer therapy with
anthracyclines, in particular with doxorubicin (DXR) being the leading drug of the group …

Anthracyclines, such as doxorubicin, are among the most valuable treatments for various
cancers, but their clinical use is limited due to detrimental side effects such as cardiotoxicity …

Rationale: Endothelial dysfunction is a characteristic feature of diabetes and obesity in
animal models and humans. Deficits in nitric oxide production by endothelial nitric oxide …

Objective To detect whether oral acetyl‐l‐carnitine might be useful in the acute and early
chronic phases of Peyronie's disease, compared with tamoxifen, a drug currently in use …

Adriamycin is a potent and broad-spectrum antineoplastic agent that plays a major role in
cancer chemotherapy. Unfortunately, its use has been hampered by conventional toxicities …

Anthracyclines play a major role in the treatment of solid malignancies, but their clinical use
is limited by acute or chronic cardiac toxicity. This is not due to the same molecular action …

Doxorubicin (DOX) has not only chronic, but also acute toxic effects in the heart, ascribed to
the generation of reactive oxygen species (ROS). Focusing on the DOX-induced early …

Glioblastoma (GBM) is highly resistant to chemotherapies, immune-based therapies, and
targeted inhibitors. To identify novel drug targets, we screened orthotopically implanted …