OBJECTIVE: Our objective was to determine the potential for chlorhexidine used as a
vaginal and neonatal wash to reduce adverse outcomes of pregnancy, especially in …

Objectives Recurrent vulvovaginal candidiasis (RVVC) causes significant morbidity.
Candida albicans is the main pathogen associated with both sporadic and recurrent …

Polyhexamethylene biguanide (PHMB) is a polybiguanide (PBG) oligomer with antimicrobial
activity that is used extensively and safely as a disinfectant. The reported mechanism of …

Background Antiseptic vaginal preparation is recommended before gynecologic surgery;
however, there is a lack of data regarding the effectiveness of different agents. Objective To …

Study Design: Vaginal swabs were collected for microbiologic analysis to characterize
normal flora. Subsequently, the vagina was exposed to either CHG or BZK twice at 24-hour …

Objective: We evaluated the efficacy and tolerability of a new chlorhexidine-based
bioadhesive vaginal gel (Clomirex*) in women with vaginal infections. Study design and …

Objective. To evaluate whether preoperative vaginal preparation routines influence
postoperative infectious morbidity in vaginal hysterectomy and to analyze risk factors for …

Background The rate of HIV transmission is increasing more in women than in any other
group. There is an urgent need for the development of microbicides with activity against this …

Background: Chlorhexidine is a disinfectant that has been used in skin and mouth washes
and as a preservative in some vaginal lubricants. A gel containing 0.25% chlorhexidine …

Background There is a continuing need to evaluate sustainable interventions for prevention
of mother-to-child transmission (MTCT) of HIV type 1. We evaluated different concentrations …