Emerging concepts in bone repair and the premise of soft materials

I Roohani, GC Yeo, SM Mithieux, AS Weiss - Current Opinion in …, 2022 - Elsevier
Human bone has a strong regenerative capacity that allows for restoration of its function and
structure after damage. For degenerative bone diseases or large defects, bone regeneration …

Collagen and elastin biomaterials for the fabrication of engineered living tissues

D Miranda-Nieves, EL Chaikof - ACS Biomaterials Science & …, 2017 - ACS Publications
Collagen and elastin represent the two most predominant proteins in the body and are
responsible for modulating important biological and mechanical properties. Thus, the focus …

Small Caliber Compliant Vascular Grafts Based on Elastin-Like Recombinamers for in situ Tissue Engineering

A Fernández-Colino, F Wolf, S Rütten… - … in bioengineering and …, 2019 - frontiersin.org
Vascular disease is a leading cause of death worldwide, but surgical options are restricted
by the limited availability of autologous vessels, and the suboptimal performance of …

Elastomers in vascular tissue engineering

MA Hiob, GW Crouch, AS Weiss - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Elastic materials can mechanically match the dynamic tissues found in the
vasculature.•Elastomers can be processed using different techniques such as casting or …

Tropoelastin implants that accelerate wound repair

SM Mithieux, B Aghaei‐Ghareh‐Bolagh… - Advanced …, 2018 - Wiley Online Library
A novel, pure, synthetic material is presented that promotes the repair of full‐thickness skin
wounds. The active component is tropoelastin and leverages its ability to promote new blood …

A sterilizable, biocompatible, tropoelastin surface coating immobilized by energetic ion activation

GC Yeo, A Kondyurin… - Journal of The …, 2017 - royalsocietypublishing.org
Biomimetic materials which integrate with surrounding tissues and regulate new tissue
formation are attractive for tissue engineering and regenerative medicine. Plasma …

Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers

A Fernandez-Colino, F Wolf, R Moreira… - European Polymer …, 2019 - Elsevier
Coronary artery disease is the leading cause of death around the world. Endovascular
stenting is the preferred treatment option to restore blood flow in the coronary arteries due to …

Vascular endothelial growth factor modified macrophages transdifferentiate into endothelial-like cells and decrease foam cell formation

D Yan, Y He, J Dai, L Yang, X Wang… - Bioscience …, 2017 - portlandpress.com
Macrophages are largely involved in the whole process of atherosclerosis from an initiation
lesion to an advanced lesion. Endothelial disruption is the initial step and macrophage …

Plasma processing of PDMS based spinal implants for covalent protein immobilization, cell attachment and spreading

DV Bax, Y Yin, A Kondyurin, AD Diwan… - Journal of Materials …, 2018 - Springer
PDMS is widely used for prosthetic device manufacture. Conventional ion implantation is not
a suitable treatment to enhance the biocompatibility of poly dimethyl siloxane (PDMS) due to …

Tropoelastin enhances nitric oxide production by endothelial cells

MA Hiob, AE Trane, SG Wise, PN Bernatchez… - …, 2016 - Taylor & Francis
Aims: This study aimed to characterize the role of tropoelastin in eliciting a nitric oxide
response in endothelial cells. Materials and methods: Nitric oxide production in cells was …