Human–mosquito contact: a missing link in our understanding of mosquito-borne disease transmission dynamics

P Thongsripong, JM Hyman, DD Kapan… - Annals of the …, 2021 - academic.oup.com
Despite the critical role that contact between hosts and vectors, through vector bites, plays in
driving vector-borne disease (VBD) transmission, transmission risk is primarily studied …

Differential attraction in mosquito–human interactions and implications for disease control

J Martinez, A Showering, C Oke… - … Transactions of the …, 2021 - royalsocietypublishing.org
Mosquito-borne diseases are a major burden on human health worldwide and their
eradication through vector control methods remains challenging. In particular, the success of …

[HTML][HTML] Human scent guides mosquito thermotaxis and host selection under naturalistic conditions

D Giraldo, S Rankin-Turner, A Corver, GM Tauxe… - Current Biology, 2023 - cell.com
Summary The African malaria mosquito Anopheles gambiae exhibits a strong innate drive to
seek out humans in its sensory environment, classically entering homes to land on human …

Pareto rules for malaria super-spreaders and super-spreading

L Cooper, SY Kang, D Bisanzio, K Maxwell… - Nature …, 2019 - nature.com
Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An
80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of …

Plasmodium falciparum infection in humans and mosquitoes influence natural Anopheline biting behavior and transmission

CF Markwalter, Z Lapp, L Abel, E Kimachas… - Nature …, 2024 - nature.com
The human infectious reservoir of Plasmodium falciparum is governed by transmission
efficiency during vector-human contact and mosquito biting preferences. Understanding …

Malaria hotspots: is there epidemiological evidence for fine-scale spatial targeting of interventions?

G Stresman, T Bousema, J Cook - Trends in parasitology, 2019 - cell.com
As data at progressively granular spatial scales become available, the temptation is to target
interventions to areas with higher malaria transmission–so-called hotspots–with the aim of …

[HTML][HTML] When is a Plasmodium-infected mosquito an infectious mosquito?

W Graumans, E Jacobs, T Bousema, P Sinnis - Trends in Parasitology, 2020 - cell.com
Plasmodium parasites experience significant bottlenecks as they transit through the
mosquito and are transmitted to their mammalian host. Oocyst prevalence on mosquito …

Genotyping of Anopheles mosquito blood meals reveals nonrandom human host selection: implications for human-to-mosquito Plasmodium falciparum transmission

RB Mbewe, JB Keven, C Mangani, ML Wilson… - Malaria Journal, 2023 - Springer
Background Control of malaria parasite transmission can be enhanced by understanding
which human demographic groups serve as the infectious reservoirs. Because vector biting …

Extreme competence: keystone hosts of infections

LB Martin, BA Addison, AGD Bean… - Trends in Ecology & …, 2019 - cell.com
Individual hosts differ extensively in their competence for parasites, but traditional research
has discounted this variation, partly because modeling such heterogeneity is difficult. This …

Modelling exposure heterogeneity and density dependence in onchocerciasis using a novel individual-based transmission model, EPIONCHO-IBM: Implications for …

JID Hamley, P Milton, M Walker… - PLoS neglected tropical …, 2019 - journals.plos.org
Background Density dependence in helminth establishment and heterogeneity in exposure
to infection are known to drive resilience to interventions based on mass drug administration …