Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options
Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide.
Despite the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of …
Despite the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of …
The epidemiology of drug‐resistant epilepsy: a systematic review and meta‐analysis
L Kalilani, X Sun, B Pelgrims, M Noack‐Rink… - …, 2018 - Wiley Online Library
Objective The definition of drug‐resistant epilepsy (DRE) affects case identification and
treatment, and impacts prevalence or incidence estimates and health burden estimation in …
treatment, and impacts prevalence or incidence estimates and health burden estimation in …
Treatment outcomes in patients with newly diagnosed epilepsy treated with established and new antiepileptic drugs: a 30-year longitudinal cohort study
Importance A study published in 2000 showed that more than one-third of adults with
epilepsy have inadequate control of seizures with antiepileptic drugs (AEDs). This study …
epilepsy have inadequate control of seizures with antiepileptic drugs (AEDs). This study …
Drug-resistant epilepsy: multiple hypotheses, few answers
Epilepsy is a common neurological disorder that affects over 70 million people worldwide.
Despite the recent introduction of new antiseizure drugs (ASDs), about one-third of patients …
Despite the recent introduction of new antiseizure drugs (ASDs), about one-third of patients …
Comorbidities of epilepsy: current concepts and future perspectives
The burden of comorbidity in people with epilepsy is high. Several diseases, including
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …
Эпилепсия у детей и взрослых женщин и мужчин
ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …
Drug resistance in epilepsy
E Perucca, P Perucca, HS White, EC Wirrell - The Lancet Neurology, 2023 - thelancet.com
Drug resistance is estimated to affect about a third of individuals with epilepsy, but its
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …
Management of psychiatric and neurological comorbidities in epilepsy
AM Kanner - Nature Reviews Neurology, 2016 - nature.com
The treatment of epileptic seizure disorders is not restricted to the achievement of seizure-
freedom, but must also include the management of comorbid medical, neurological …
freedom, but must also include the management of comorbid medical, neurological …
Epilepsy, antiepileptic drugs, and aggression: an evidence-based review
Antiepileptic drugs (AEDs) have many benefits but also many side effects, including
aggression, agitation, and irritability, in some patients with epilepsy. This article offers a …
aggression, agitation, and irritability, in some patients with epilepsy. This article offers a …
Epilepsy, suicidality, and psychiatric disorders: a bidirectional association
DC Hesdorffer, L Ishihara, L Mynepalli… - Annals of …, 2012 - Wiley Online Library
Objective: A study was undertaken to determine whether psychiatric disorders associated
with suicide are more common in incident epilepsy than in matched controls without …
with suicide are more common in incident epilepsy than in matched controls without …