NAFLD and NASH in postmenopausal women: implications for diagnosis and treatment

JK DiStefano - Endocrinology, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) prevalence in women is increasing worldwide.
Women of reproductive age have lower rates of NAFLD compared with men; however, this …

Role of estrogens in the regulation of liver lipid metabolism

BT Palmisano, L Zhu, JM Stafford - Sex and gender factors affecting …, 2017 - Springer
Before menopause, women are protected from atherosclerotic heart disease associated with
obesity relative to men. Sex hormones have been proposed as a mechanism that …

[HTML][HTML] Sex differences in lipid and lipoprotein metabolism

BT Palmisano, L Zhu, RH Eckel, JM Stafford - Molecular metabolism, 2018 - Elsevier
Background Endogenous sex hormones are important for metabolic health in men and
women. Before menopause, women are protected from atherosclerotic cardiovascular …

Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element

Y Hou, S Zhang, L Wang, J Li, G Qu, J He, H Rong, H Ji… - Gene, 2012 - Elsevier
Iron is essential for the human being, involving in oxygen transport, energy metabolism and
DNA synthesis. Iron homeostasis is tightly governed by the hepcidin–ferroportin axis, of …

The dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 receptor agonist tirzepatide effects on body weight evolution, adiponectin, insulin …

PH Reis‐Barbosa… - Diabetes, Obesity …, 2024 - Wiley Online Library
Abstract Aim Tirzepatide (Tzp), a novel dual agonist glucose‐dependent insulinotropic
polypeptide/glucagon‐like peptide‐1, is approved for treating insulin resistance and obesity …

The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause

R Robeva, D Mladenović, M Vesković, D Hrnčić… - Maturitas, 2021 - Elsevier
The hypoestrogenic period after menopause and associated metabolic imbalance might
facilitate the onset of non-alcoholic fatty liver disease (NAFLD) and its progression. The …

The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women

E Molina‐Molina, GE Furtado, JG Jones… - European Journal of …, 2022 - Wiley Online Library
Background The prevalence and severity of nonalcoholic fatty liver disease (NAFLD)
increase in women after menopause. This narrative review discusses the causes and …

[HTML][HTML] Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes

DA Antelo-Cea, L Martínez-Rojas… - International Journal of …, 2024 - mdpi.com
Obesity and type 2 diabetes (T2D) are widespread metabolic disorders that significantly
impact global health today, affecting approximately 17% of adults worldwide with obesity …

Salvia officinalis mitigates uterus and liver damages induced by an estrogen deficiency in ovariectomized rats

F Koubaa‐Ghorbel, M Chaâbane… - Journal of Food …, 2021 - Wiley Online Library
The present study evaluated the antioxidant activity of Salvia officinalis (sage) and its
protective effect on estrogen deficiency in ovariectomized rats. Female Wistar rats were …

Sexual dimorphism in the age-induced insulin resistance, liver steatosis, and adipose tissue function in rats

F Garcia-Carrizo, T Priego, N Szostaczuk… - Frontiers in …, 2017 - frontiersin.org
Age-linked metabolic disturbances, such as liver steatosis and insulin resistance, show
greater prevalence in men than in women. Thus, our aim was to analyze these sex-related …