Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β‐Cell Dysfunction
The prevalence of diabetes mellitus (DM) is increasing worldwide, a consequence of the
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …
An updated review on anti-diabetic agents and their functions: a comparative study
A Hussain, A Latif, Z Rehmat… - … in Life Sciences, 2023 - submission.als-journal.com
Chronic metabolic disease is considered by a high concentration of glucose in the blood
consequent from imperfections in insulin secretion or insulin action. Currently, it is rapidly …
consequent from imperfections in insulin secretion or insulin action. Currently, it is rapidly …
Insulin receptor substrate 1 gene and glucose metabolism characteristics in type 2 diabetes mellitus with comorbidities
M Marushchak, I Krynytska - Ethiopian Journal of Health Sciences, 2021 - ajol.info
BACKGROUND፡ Genetic variants that affect insulin signaling play an important role in
insulin resistance (IR) in type 2 diabetes mellitus (T2DM). This study aimed to evaluate …
insulin resistance (IR) in type 2 diabetes mellitus (T2DM). This study aimed to evaluate …
Genetic association of insulin receptor substrate-1 (IRS-1, rs1801278) gene with insulin resistant of type 2 diabetes mellitus in a Pakistani population
Insulin resistance (IR), a pathological condition of type 2 diabetes mellitus (T2DM) is
characterized by an inability of body's tissue to respond the secreted or administered insulin …
characterized by an inability of body's tissue to respond the secreted or administered insulin …
Differential expression of insulin receptor substrate-1 (IRS-1) in visceral and subcutaneous adipose depots of morbidly obese subjects undergoing bariatric surgery in …
M Sharma, S Aggarwal, U Nayar, NK Vikram… - Diabetes & Metabolic …, 2021 - Elsevier
Background/aim: Abdominal obesity and associated metabolic consequences are a
burgeoning problem in Asian Indians and studying their genetic predisposition is important …
burgeoning problem in Asian Indians and studying their genetic predisposition is important …
Association of IRS1 (Gly972Arg) and IRS2 (Gly1057Asp) genes polymorphisms with OSA and NAFLD in Asian Indians
SP Bhatt, R Guleria - PloS one, 2021 - journals.plos.org
Aim and objective The aim of the study was to investigate the relationships between insulin
receptor substrate (IRS) 1 (Gly972Arg) and IRS2 (Gly1057Asp) genes with obstructive sleep …
receptor substrate (IRS) 1 (Gly972Arg) and IRS2 (Gly1057Asp) genes with obstructive sleep …
Association of IRS1 genetic variants with glucose control and insulin resistance in type 2 diabetic patients from Bosnia and Herzegovina
L Mahmutovic, T Bego, M Sterner… - Drug Metabolism and …, 2019 - degruyter.com
Background Previous studies reported conflicting results regarding association of insulin
receptor substrate 1 (IRS1) gene variation with type 2 diabetes (T2D) and insulin resistance …
receptor substrate 1 (IRS1) gene variation with type 2 diabetes (T2D) and insulin resistance …
The importance of precision medicine in type 2 diabetes mellitus (T2DM): from pharmacogenetic and pharmacoepigenetic aspects
F Khatami, MR Mohajeri-Tehrani… - … , Metabolic & Immune …, 2019 - ingentaconnect.com
Background: Type 2 Diabetes Mellitus (T2DM) is a worldwide disorder as the most important
challenges of health-care systems. Controlling the normal glycaemia greatly profit long-term …
challenges of health-care systems. Controlling the normal glycaemia greatly profit long-term …
Associations between two single-nucleotide polymorphisms (rs1801278 and rs2943641) of insulin receptor substrate 1 gene and type 2 diabetes susceptibility: a meta …
Q Li, Y Qiao, C Wang, G Zhang, X Zhang, L Xu - Endocrine, 2016 - Springer
The objective of the study is to assess the association between rs1801278 and rs2943641 of
insulin receptor substrate 1 gene (IRS1) and the susceptibility to type 2 diabetes. A literature …
insulin receptor substrate 1 gene (IRS1) and the susceptibility to type 2 diabetes. A literature …
Genetic markers predicting sulphonylurea treatment outcomes in type 2 diabetes patients: current evidence and challenges for clinical implementation
NK Loganadan, HZ Huri, SR Vethakkan… - The pharmacogenomics …, 2016 - nature.com
The clinical response to sulphonylurea, an oral antidiabetic agent often used in combination
with metformin to control blood glucose in type 2 diabetes (T2DM) patients, has been widely …
with metformin to control blood glucose in type 2 diabetes (T2DM) patients, has been widely …