[HTML][HTML] Autoimmune hepatitis, one disease with many faces: etiopathogenetic, clinico-laboratory and histological characteristics

NK Gatselis, K Zachou, GK Koukoulis… - World journal of …, 2015 - ncbi.nlm.nih.gov
Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology
characterized by hypergammaglobulinemia, autoantibodies detection and interface …

autoimmune hepatitis–current management and challenges

K Zachou, P Muratori, GK Koukoulis… - Alimentary …, 2013 - Wiley Online Library
Background Autoimmune hepatitis (AIH) is a disease of unknown aetiology characterised by
interface hepatitis, hypergammaglobulinaemia, circulating autoantibodies and a favourable …

Autoimmune hepatitis: a comprehensive review

R Liberal, CR Grant, G Mieli-Vergani, D Vergani - Journal of autoimmunity, 2013 - Elsevier
Autoimmune hepatitis (AIH) is an immune-mediated liver disorder characterised by female
preponderance, elevated transaminase and immunoglobulin G levels, seropositivity for …

Regulatory T cell and forkhead box protein 3 as modulators of immune homeostasis

LMS Pereira, STM Gomes, R Ishak… - Frontiers in …, 2017 - frontiersin.org
The transcription factor forkhead box protein 3 (FOXP3) is an essential molecular marker of
regulatory T cell (Treg) development in different microenvironments. Tregs are cells …

[PDF][PDF] A novel “humanized mouse” model for autoimmune hepatitis and the association of gut microbiota with liver inflammation

M Yuksel, Y Wang, N Tai, J Peng, J Guo, K Beland… - …, 2015 - Wiley Online Library
Autoimmune hepatitis (AIH) in humans is a severe inflammatory liver disease characterized
by interface hepatitis, the presence of circulating autoantibodies, and hyper …

Regulatory T cells in autoimmune hepatitis: unveiling their roles in mouse models and patients

H Wang, X Feng, W Yan, D Tian - Frontiers in Immunology, 2020 - frontiersin.org
Autoimmune hepatitis (AIH) is a severe and chronic liver disease, and its incidence has
increased worldwide in recent years. Research into the pathogenesis of AIH remains limited …

The effects of androgens on T cells: clues to female predominance in autoimmune liver diseases?

L Henze, D Schwinge, C Schramm - Frontiers in immunology, 2020 - frontiersin.org
The immune system responds differently in women and in men. Generally speaking, adult
females show stronger innate and adaptive immune responses than males. This results in …

[PDF][PDF] Depletion of B cells induces remission of autoimmune hepatitis in mice through reduced antigen presentation and help to T cells

K Béland, G Marceau, A Labardy, S Bourbonnais… - …, 2015 - Wiley Online Library
Autoimmune hepatitis (AIH) is known as a T cell–mediated disease. However, AIH patients
refractory to conventional treatment have been successfully treated with anti‐CD20 …

[PDF][PDF] Adoptive transfer of ex vivo expanded regulatory T cells in an autoimmune hepatitis murine model restores peripheral tolerance

P Lapierre, K Béland, R Yang, F Alvarez - Hepatology, 2013 - Wiley Online Library
Autoimmune hepatitis (AIH) is characterized by a loss of immunological tolerance to
hepatocytes. Patients respond well to immunosuppression but progression to endstage liver …

The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis

M Liang, Z Liwen, Z Yun, D Yanbo… - Journal of immunology …, 2018 - Wiley Online Library
This study is aimed at examining the potential role of regulatory T‐(Treg‐) Th1‐Th17‐Th22
cells in the pathogenic process of autoimmune hepatitis (AIH). The numbers of Foxp3+ …