Biochemical and genetic analysis identify CSLD3 as a beta-1, 4-glucan synthase that functions during plant cell wall synthesis

J Yang, G Bak, T Burgin, WJ Barnes, HB Mayes… - The Plant …, 2020 - academic.oup.com
In plants, changes in cell size and shape during development fundamentally depend on the
ability to synthesize and modify cell wall polysaccharides. The main classes of cell wall …

The evolution of function within the Nudix homology clan

JR Srouji, A Xu, A Park, JF Kirsch… - Proteins: Structure …, 2017 - Wiley Online Library
The Nudix homology clan encompasses over 80,000 protein domains from all three
domains of life, defined by homology to each other. Proteins with a domain from this clan fall …

In Silico Identification of Mimicking Molecules as Defense Inducers Triggering Jasmonic Acid Mediated Immunity against Alternaria Blight Disease in Brassica …

RK Pathak, M Baunthiyal, R Shukla, D Pandey… - Frontiers in plant …, 2017 - frontiersin.org
Alternaria brassicae and Alternaria brassicicola are two major phytopathogenic fungi which
cause Alternaria blight, a recalcitrant disease on Brassica crops throughout the world, which …

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity

I Iordanov, C Mihalyi, B Toth, L Csanady - Elife, 2016 - elifesciences.org
Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca2+-permeable cation channel
essential for immunocyte activation, insulin secretion, and postischemic cell death. TRPM2 …

Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform

SA Shumar, EW Kerr, WJ Geldenhuys… - Journal of Biological …, 2018 - ASBMB
CoA is the major acyl carrier in mammals and a key cofactor in energy metabolism. Dynamic
regulation of CoA in different tissues and organs supports metabolic flexibility. Two …

Structural analyses of NudT16–ADP-ribose complexes direct rational design of mutants with improved processing of poly (ADP-ribosyl) ated proteins

P Thirawatananond, RL McPherson, J Malhi… - Scientific reports, 2019 - nature.com
ADP-ribosylation is a post-translational modification that occurs on chemically diverse amino
acids, including aspartate, glutamate, lysine, arginine, serine and cysteine on proteins and is …

Impact of Environmental Sub-Inhibitory Concentrations of Antibiotics, Heavy Metals, and Biocides on the Emergence of Tolerance and Effects on the Mutant Selection …

KB Chukwu, OA Abafe, DG Amoako, A Ismail… - Microorganisms, 2023 - mdpi.com
Bacteria's ability to withstand the detrimental effects of antimicrobials could occur as
resistance or tolerance with the minimum inhibitory concentration, the mutant prevention …

NudC Nudix hydrolase from Pseudomonas syringae, but not its counterpart from Pseudomonas aeruginosa, is a novel regulator of intracellular redox balance …

M Modzelan, M Kujawa, K Głąbski… - Molecular …, 2014 - Wiley Online Library
Nudix pyrophosphatases, ubiquitous in all organisms, have not been well studied. Recent
implications that some of them may be involved in response to stress and in pathogenesis …

Nudix‐type RNA pyrophosphohydrolase provides homeostasis of virulence factor pyocyanin and functions as a global regulator in Pseudomonas aeruginosa

M Kujawa, M Lirski, M Ziecina, J Drabinska… - Molecular …, 2017 - Wiley Online Library
The PA0336 protein from Pseudomonas aeruginosa belongs to the family of widely
distributed Nudix pyrophosphohydrolases, which catalyze the hydrolysis of pyrophosphate …

On the helical arrangements of protein molecules

Z Dauter, M Jaskolski - Protein Science, 2018 - Wiley Online Library
Helical structures are prevalent in biology. In the PDB, there are many examples where
protein molecules are helically arranged, not only according to strict crystallographic screw …