Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases

ARH van Zanten, E De Waele, PE Wischmeyer - Critical Care, 2019 - Springer
Background Although mortality due to critical illness has fallen over decades, the number of
patients with long-term functional disabilities has increased, leading to impaired quality of …

Sepsis-associated hyperlactatemia

M Garcia-Alvarez, P Marik, R Bellomo - Critical care, 2014 - Springer
There is overwhelming evidence that sepsis and septic shock are associated with
hyperlactatemia (sepsis-associated hyperlactatemia (SAHL)). SAHL is a strong independent …

Energetic dysfunction in sepsis: a narrative review

S Preau, D Vodovar, B Jung, S Lancel, L Zafrani… - Annals of Intensive …, 2021 - Springer
Background Growing evidence associates organ dysfunction (s) with impaired metabolism
in sepsis. Recent research has increased our understanding of the role of substrate …

Metabolic response to the stress of critical illness

JC Preiser, C Ichai, JC Orban… - British journal of …, 2014 - academic.oup.com
The metabolic response to stress is part of the adaptive response to survive critical illness.
Several mechanisms are well preserved during evolution, including the stimulation of the …

Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19

J Whittle, J Molinger, D MacLeod, K Haines… - Critical Care, 2020 - Springer
COVID-19 infection results in respiratory failure requiring ICU care in a small, yet significant,
number of patients [1]. The longitudinal metabolic phenotype and energy expenditure of this …

A rational approach to fluid therapy in sepsis

P Marik, R Bellomo - BJA: British Journal of Anaesthesia, 2016 - academic.oup.com
Aggressive fluid resuscitation to achieve a central venous pressure (CVP) greater than 8 mm
Hg has been promoted as the standard of care, in the management of patients with severe …

[HTML][HTML] Nutrition, anabolism, and the wound healing process: an overview

RH Demling - Eplasty, 2009 - ncbi.nlm.nih.gov
Objective: To develop a clear, concise, and up-to-date treatise on the role of anabolism from
nutrition in wound healing. Special emphasis was to be placed on the effect of the stress …

Alterations in fuel metabolism in critical illness: hyperglycaemia

BA Mizock - Best Practice & Research Clinical Endocrinology & …, 2001 - Elsevier
Hyperglycaemia is common during critical illness and may be viewed teleologically as a
means of ensuring an adequate supply of glucose for the brain and phagocytic cells. Under …

Nutrition in sepsis: a bench-to-bedside review

E De Waele, MLNG Malbrain, H Spapen - Nutrients, 2020 - mdpi.com
Nutrition therapy in sepsis is challenging and differs from the standard feeding approach in
critically ill patients. The dysregulated host response caused by infection induces …

Nutrition therapy in sepsis

P Wischmeyer - Critical care clinics, 2017 - pmc.ncbi.nlm.nih.gov
Sepsis is characterized by characterized by early massive catabolism, lean body mass
(LBM) loss and escalating hypermetabolism persisting for months to years. Early enteral …