Optic neuritis is an inflammatory optic neuropathy that is commonly indicative of autoimmune
neurological disorders including multiple sclerosis, myelin-oligodendrocyte glycoprotein …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Oligodendrocyte precursors (OPs) continue to proliferate and generate myelinating
oligodendrocytes (OLs) well into adulthood. It is not known whether adult-born OLs …

Background The human monoclonal antibody opicinumab (BIIB033, anti-LINGO-1) has
shown remyelinating activity in preclinical studies. We therefore assessed the safety and …

Background Vision loss after optic neuropathy is considered irreversible. Here, repetitive
transorbital alternating current stimulation (rtACS) was applied in partially blind patients with …

Evoked potentials (EP) characterize signal conduction in selected tracts of the central
nervous system in a quantifiable way. Since alteration of signal conduction is the main …

Idiopathic demyelinating optic neuritis (ON) most commonly presents as acute unilateral
vision loss and eye pain and is frequently associated with multiple sclerosis. Although …

Abstract From the Section Editor: The next two installments in the JNO “Disease of the Year:
Multiple Sclerosis” series focus on lessons that can be learned form the afferent visual …

Multiple sclerosis (MS) is a disease of the central nervous system (CNS) believed to arise
from a dysfunctional immune‐mediated response in a genetically susceptible host. The …

Dynamic visual acuity test (DVAT) plays a key role in the assessment of vestibular function,
the visual function of athletes, as well as various ocular diseases. As the visual pathways …