Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Periodontitis is a disease characterized by tooth‐associated microbial biofilms that drive
chronic inflammation and destruction of periodontal‐supporting tissues. In some individuals …

Epigenetic mechanisms, namely DNA and histone modifications, are critical regulators of
immunity and inflammation which have emerged as potential targets for immunomodulating …

Periodontitis is characterized by irreversible destruction of periodontal tissue. At present, the
accepted etiology of periodontitis is based on a three-factor theory including pathogenic …

Aim To explore the M1/M2 status of macrophage polarization from healthy, gingivitis, and
periodontitis patient samples. Materials and methods Gingival biopsies were collected from …

The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …

Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between
commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in …

Objectives The mechanisms involved in the initiation and progression of peri‐implantitis
lesions are poorly understood. It was the aim to determine the content and activation status …

Background: Periodontitis is a chronic inflammatory disease involving an interplay between
bacteria, inflammation, host response genes, and environmental factors. The manifestation …

Emerging evidence suggests comprehensive immune profiling represents a highly
promising, yet insufficiently tapped approach to identify potentially prognostic signatures for …