The blood vessels vascularizing the central nervous system exhibit a series of distinct
properties that tightly control the movement of ions, molecules, and cells between the blood …

Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …

Blood vessels in the CNS form a specialized and critical structure, the blood–brain barrier
(BBB). We present a resource to understand the molecular mechanisms that regulate BBB …

Vascular endothelial cells in the central nervous system (CNS) form a barrier that restricts
the movement of molecules and ions between the blood and the brain. This blood–brain …

The blood–brain barrier (BBB) is a term used to describe a series of properties possessed
by the vasculature of the central nervous system (CNS) that tightly regulate the movement of …

The fertility and survival of an individual rely on the ability of the periphery to promptly,
effectively, and reproducibly communicate with brain neural networks that control …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

The delivery of blood-borne molecules conveying metabolic information to neural networks
that regulate energy homeostasis is restricted by brain barriers. The fenestrated endothelium …

The vascular system has the critical function of supplying tissues with nutrients and clearing
waste products. To accomplish these goals, the vasculature must be sufficiently permeable …