Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, versus tetanus–diphtheria–acellular pertussis vaccine: a randomised, double …

C Keech, VE Miller, B Rizzardi, C Hoyle, MJ Pryor… - The Lancet, 2023 - thelancet.com
Background Bordetella pertussis epidemics persist as transmission remains unabated
despite high acellular pertussis vaccination rates. BPZE1, a live attenuated intranasal …

Understanding the functional role of the microbiome and metabolome in asthma

C Cobos-Uribe, ME Rebuli - Current Allergy and Asthma Reports, 2023 - Springer
Abstract Purpose of Review Asthma is a heterogenous respiratory disease characterized by
airway inflammation and obstruction. However, the causes of asthma are unknown. Several …

Utilization of nasal mucus to investigate the pathophysiology of chronic rhinosinusitis

M Parra-Ferro, JM Justice, BC Lobo… - American Journal of …, 2022 - journals.sagepub.com
Background Nasal mucus is proving to be a useful means by which to study the
pathogenesis of chronic rhinosinusitis (CRS). Given the increase in publications examining …

Electronic-cigarette use alters nasal mucosal immune response to live-attenuated influenza virus. A clinical trial

ME Rebuli, E Glista-Baker, JR Hoffman… - American journal of …, 2021 - atsjournals.org
Inhalation of tobacco smoke has been linked to increased risk of viral infection, such as
influenza. Inhalation of electronic-cigarette (e-cigarette) aerosol has also recently been …

[HTML][HTML] Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction

MD Kim, S Chung, JS Dennis, M Yoshida… - Frontiers in …, 2022 - frontiersin.org
Vegetable glycerin (VG) and propylene glycol (PG) serve as delivery vehicles for nicotine
and flavorings in most e-cigarette (e-cig) liquids. Here, we investigated whether VG e-cig …

Wood smoke exposure alters human inflammatory responses to viral infection in a sex-specific manner. A randomized, placebo-controlled study

ME Rebuli, AM Speen, EM Martin, KA Addo… - American journal of …, 2019 - atsjournals.org
Rationale: Exposure to particulates from burning biomass is an increasing global health
issue. Burning biomass, including wood smoke, is associated with increased lower …

Multiplex hybrid antigen-capture LC-MRM quantification in sera and nasal lining fluid of AZD7442, a SARS-CoV-2-targeting antibody combination

R Mu, Y Huang, J Bouquet, J Yuan, RJ Kubiak… - Analytical …, 2022 - ACS Publications
AZD7442 (tixagevimab [AZD8895]/cilgavimab [AZD1061]) is a monoclonal antibody (mAb)
combination in development for the prevention and treatment of coronavirus disease 2019 …

Malondialdehyde in nasal fluid: a biomarker for monitoring asthma control in relation to air pollution exposure

L He, X Cui, Z Li, Y Teng, KK Barkjohn… - Environmental …, 2020 - ACS Publications
Fine particulate matter (PM2. 5) and ozone (O3) may exert oxidative damage in the nose,
which is hypothesized to be associated with worsened asthma symptoms. This study, hence …

[HTML][HTML] Association between short-term exposure to PM2. 5 and nasal microbiota dysbiosis, inflammation and oxidative stress: A panel study of healthy young adults

W Li, B Sun, H Li, Z An, J Li, J Jiang, J Song… - … and Environmental Safety, 2023 - Elsevier
Abstract Fine particulate matter (PM 2.5) is the primary environmental stressor and a
significant threat to public health. However, the effect of PM 2.5 exposure on human nasal …

[HTML][HTML] Associations of short-term PM2. 5 exposures with nasal oxidative stress, inflammation and lung function impairment and modification by GSTT1-null genotype …

B Sun, J Song, Y Wang, J Jiang, Z An, J Li… - Environmental …, 2021 - Elsevier
Abstract PM 2.5 (particulate matter≤ 2.5 μm in aerodynamic diameter) is a major urban air
pollutant worldwide. Its effects on the respiratory system of the susceptible population have …