Endogenous, very small embryonic-like stem cells: critical review, therapeutic potential and a look ahead

D Bhartiya, A Shaikh, S Anand, H Patel… - Human …, 2017 - academic.oup.com
BACKGROUND Both pluripotent very small embryonic-like stem cells (VSELs) and induced
pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for …

Stem cells, pluripotency and glial cell markers in peripheral blood of bipolar patients on long-term lithium treatment

E Ferensztajn-Rochowiak, J Kucharska-Mazur… - Progress in Neuro …, 2018 - Elsevier
Background We investigated the effect of long-term lithium treatment on very-small
embryonic-like stem cells (VSELs) and the mRNA expression of pluripotency and glial …

Similar population of CD133+ and DDX4+ VSEL-like stem cells sorted from human embryonic stem cell, ovarian, and ovarian cancer ascites cell cultures: the real …

I Virant-Klun, P Skerl, S Novakovic, E Vrtacnik-Bokal… - Cells, 2019 - mdpi.com
A population of small stem cells with diameters of up to 5 μm resembling very small
embryonic-like stem cells (VSELs) were sorted from human embryonic stem cell (hESC) …

Promoting motor functions in a spinal cord injury model of rats using transplantation of differentiated human olfactory stem cells: A step towards future therapy

HG Hamidabadi, S Simorgh, SK Kamrava… - Behavioural Brain …, 2021 - Elsevier
Human olfactory ecto-mesenchymal stem cells (hOE-MSCs) derived from the human
olfactory mucosa (OM) can be easily isolated and expanded in cultures while their immense …

Bone marrow-derived VSELs engraft as lung epithelial progenitor cells after bleomycin-induced lung injury

AK Ciechanowicz, K Sielatycka, M Cymer, M Skoda… - Cells, 2021 - mdpi.com
Background: Alveolar type 2 (AT2) cells and bronchioalveolar stem cells (BASC) perform
critical regenerative functions in response to lung damage. Published data show that …

Proteomic analysis of murine bone marrow very small embryonic-like stem cells at steady-state conditions and after in vivo stimulation by nicotinamide and follicle …

V Chumak, K Sielatycka, A Ciechanowicz… - Stem Cell Reviews and …, 2023 - Springer
Very small embryonic-like stem cells (VSELs) are a dormant population of development
early stem cells deposited in adult tissues that as demonstrated contribute to tissue/organ …

Matrigel enhances differentiation of human adipose tissue-derived stem cells into dopaminergic neuron

F Absalan, MS Pasandi, HG Hamidabadi… - Neuroscience …, 2021 - Elsevier
Background Therapy based stem cells have offered a novel therapeutic approach for the
improvement of neurodegenerative diseases, specially Parkinson. Hence, developing a well …

Role of adult tissue-derived pluripotent stem cells in bone regeneration

L Leppik, K Sielatycka, D Henrich, Z Han… - Stem Cell Reviews and …, 2020 - Springer
Background Bone marrow-derived mononuclear cells (BM-MNC) consist of a
heterogeneous mix of mesenchymal stem cells (MSC), hematopoietic progenitor cells …

The effect of long-term lithium treatment of bipolar disorder on stem cells circulating in peripheral blood

E Ferensztajn-Rochowiak… - The World Journal of …, 2017 - Taylor & Francis
Objectives: To investigate the effect of long-term lithium treatment on very small embryonic-
like stem cells (VSELs), haematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs) …

The potential role of very small embryonic-like stem cells in the neuroinflammation induced by social isolation stress: Introduction of a new paradigm

A Haj-Mirzaian, A Khosravi, A Haj-Mirzaian… - Brain Research …, 2020 - Elsevier
Lack of social contacts could induce psychiatric features and lead to various behavioral and
neurochemical abnormalities in rodents. Social isolation stress (SIS) is a valid paradigm of …