Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

Microvilli are actin-based structures found on the apical aspect of many epithelial cells. In
this review, we discuss different types of microvilli, as well as comparisons with actin-based …

Mitochondrial division, essential for survival in mammals, is enhanced by an inter-organellar
process involving ER tubules encircling and constricting mitochondria. The force for …

The vertebrate small intestine requires an enormous surface area to effectively absorb
nutrients from food. Morphological adaptations required to establish this extensive surface …

Two proteins implicated in inherited deafness, myosin IIIa, a plus-end-directed motor, and
espin,,,, an actin-bundling protein containing the actin-monomer-binding motif WH2, have …

Dynamic communication between integrin-containing complexes (focal adhesions, FAs) and
actin filaments is critical for regulating cell adhesion. Pseudokinase ILK plays a key role in …

Transporting epithelial cells like those that line the gut build large arrays of actin-supported
protrusions called microvilli, which extend from the apical surface into luminal spaces to …

Inner ear hair cells assemble mechanosensitive hair bundles on their apical surface that
transduce sounds and accelerations. Each hair bundle is comprised of∼ 100 individual …

Hearing and vestibular function depend on mechanosensory staircase collections of hair
cell stereocilia, which are produced from microvillus-like precursors as their parallel actin …

In the development and differentiation of stem cells, mechanical forces associated with
filamentous actin (F-actin) play a crucial role. The present review aims to reveal the …