Qingre Xingyu recipe exerts inhibiting effects on ulcerative colitis development by inhibiting TNFα/NLRP3/Caspase-1/IL-1β pathway and macrophage M1 polarization

L Ning, N Ye, B Ye, Z Miao, T Cao, W Lu, D Xu… - Cell Death …, 2023 - nature.com
As a chronic inflammatory bowel disease, ulcerative colitis (UC) imposes a significant
burden on public healthcare worldwide due to its increasing morbidity. Chinese medicines …

Corticosteroids in inflammatory bowel disease: are they still a therapeutic option?

R Quera, P Núñez, B Sicilia, L Flores… - … y Hepatología (English …, 2023 - Elsevier
Despite the development and incorporation of new therapeutic strategies, such as biologic
therapy and small molecules, corticosteroids still play an important role in inducting …

Acute severe ulcerative colitis: management advice for internal medicine and emergency physicians

K Rosiou, CP Selinger - Internal and Emergency Medicine, 2021 - Springer
Acute severe ulcerative colitis is a medical emergency that warrants in-patient management.
This is best served within a multidisciplinary team setting in specialised centres or with …

[PDF][PDF] 白头翁皂苷B4 基于调节巨噬细胞极化对小鼠溃疡性结肠炎的影响

孙洁, 史肖华, 李彩云, 季士亮 - 中国医药导报 - yiyaodaobao.com.cn
目的探究白头翁皂背B4 基于调节巨噬细胞极化对葡聚糖硫酸钠(DSS) 诱导的溃疡性结肠炎(UC)
小鼠的作用, 方法将40 只SPF 级雄性C57BL/6 小鼠(体重18; 20 g) 按随机数字表法分为对照组 …

A simple emergency department-based score predicts complex hospitalization in patients with inflammatory bowel disease

A Verma, S Varma, DE Freedberg… - Digestive diseases and …, 2022 - Springer
Abstract Background and Aims Thirty percent of inflammatory bowel disease (IBD) patients
hospitalized with flare require salvage therapy or surgery. Additionally, 40% experience …

[HTML][HTML] Corticoides en la enfermedad inflamatoria intestinal:¿ siguen siendo una opción terapéutica?

R Quera, P Núñez, B Sicilia, L Flores… - Gastroenterología y …, 2023 - Elsevier
A pesar del desarrollo y de la incorporación de nuevas estrategias terapéuticas, como son
la terapia biológica y las moléculas pequeñas, los corticoides aún cumplen un papel …

Vedolizumab as Rescue Therapy in Carboplatin-Gemcitabine-Induced Triggered Acute Severe Ulcerative Colitis Flare-Up

R Pellegrino, M Fasano, F Morgillo, G Palladino… - Gastrointestinal …, 2023 - mdpi.com
Approximately 20% of patients with ulcerative colitis (UC) develop acute severe UC (ASUC),
for which intravenous systemic steroid therapy and possibly infliximab-based rescue therapy …

Management of acute severe ulcerative colitis in Chile: Experience of a multidisciplinary team

EP de Arce, R Quera, P Núñez… - Gastroenterologia …, 2022 - pubmed.ncbi.nlm.nih.gov
Management of acute severe ulcerative colitis in chile: Experience of a multidisciplinary
team Management of acute severe ulcerative colitis in chile: Experience of a …

[PDF][PDF] 溃疡性结肠炎组织中PKM2 水平及其与病情和预后的相关性分析

赵晓宇, 石飞飞, 孙文娟 - 医学临床研究 - journal07.magtech.org.cn
[目的] 探讨溃疡性结肠炎(UC) 肠组织中M2 型丙酮酸激酶(PKM2) 水平及其与患者预后的关系.[
方法] 选择2016 年6 月至2019 年11 月本院收治的103 例UC 患者(观察组) …

UPLC-QE-MS 联合网络药理学分析补中益气丸治疗溃疡性结肠炎的机制及实验验证

苏欣, 罗琳 - 中国临床药理学与治疗学, 2024 - manu41.magtech.com.cn
目的: 在网络药理学和实验验证的基础上, 探讨补中益气丸在治疗溃疡性结肠炎中的作用机制.
方法: 采用UPLC-QE-MS 对补中益气丸进行定性分析. 从GeneCards 中检索到化学成分和疾病 …