HFIP in organic synthesis

HF Motiwala, AM Armaly, JG Cacioppo… - Chemical …, 2022 - ACS Publications
1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Recent Advances of Cinnamic Acids in Organic Synthesis

L Chen, L Zhang, G Yan… - Asian Journal of Organic …, 2020 - Wiley Online Library
The great success of cinnamic acids was rooted in their multiple functional groups. Herein,
reactions triggered by the radical addition, electrophilic addition, Michael addition and …

HFIP solvent enables alcohols to act as alkylating agents in stereoselective heterocyclization

Y Zhu, I Colomer, AL Thompson… - Journal of the American …, 2019 - ACS Publications
A new method for the stereoselective synthesis of highly functionalized oxygen heterocycles
using allyl or benzyl alcohols as alkylating agents is presented. The process is efficient and …

Modular Synthesis of 9,10-Dihydroacridines through an ortho-C Alkenylation/Hydroarylation Sequence between Anilines and Aryl Alkynes in Hexafluoroisopropanol

S Wang, G Force, JF Carpentier, Y Sarazin… - Organic …, 2021 - ACS Publications
9, 10-Dihydroacridines are frequently encountered as key scaffolds in OLEDs. However,
accessing those compounds from feedstock precursors typically requires multiple steps …

Direct activation of alcohols via perrhenate ester formation for an intramolecular dehydrative Friedel–Crafts reaction

Y Zheng, X Fang, WH Deng, B Zhao… - Organic Chemistry …, 2022 - pubs.rsc.org
This manuscript describes a general method for the intramolecular dehydrative Friedel–
Crafts reaction of alcohols catalyzed by Re2O7 in hexafluoroisopropanol (HFIP). Under the …

Domino synthetic strategy for tetrahydrothiopyran derivatives from benzaldehydes, 2-acetylfuran/2-acetylthiophene, and sodium sulfide

D Chen, W Du, X Yang, T Liu - The Journal of Organic Chemistry, 2020 - ACS Publications
A novel domino reaction from benzaldehydes and 2-acetylfuran/2-acetylthiophene with
sodium sulfide was developed to synthesize a series of tetrahydrothiopyran (THTP) …

[PDF][PDF] SYNTHETIC APPROACHES TO 4-ARYL-3, 4-DIHYDROCOUMARINS

SS Yadav, J Sharma, SB Khandekar, RA Fernandes - soc.chim.it
The transformations mediated by transition metals or organocatalyzed or metal-free
strategies have become crucial tools for the synthesis of natural products and valuable …

Ösztránvázas Aza-És Oxaciklusos Vegyületek Régiószelektív Szintézise

M Barnabás - 2022 - search.proquest.com
Molnár Barnabás Page 1 ÖSZTRÁNVÁZAS AZA- ÉS OXACIKLUSOS VEGYÜLETEK
RÉGIÓSZELEKTÍV SZINTÉZISE DOKTORI ÉRTEKEZÉS Molnár Barnabás TÉMAVEZETŐ …

Эстрогены и антиэстрогены. Современные синтетические подходы к направленной модификации стероидов ряда эстра-1, 3, 5 (10)-триена: цели, реакции и …

ЮВ Кузнецов, ИС Левина, ИВ Заварзин - 2021 - elibrary.ru
В монографии обобщены сведения за последние 20 лет о широко применяемых в
настоящее время и перспективных методах синтеза производных эстра-1, 3, 5 (10) …

Six-membered ring systems: with O and/or S atoms

CMM Santos, AMS Silva - Progress in Heterocyclic Chemistry, 2020 - Elsevier
The most interesting chemistry published in 2018 on the synthesis of O-and S-6-membered
heterocycles is reviewed. This personal overview is focused on the developments made on …