Women at altitude: Sex-related physiological responses to exercise in hypoxia

A Raberin, J Burtscher, T Citherlet, G Manferdelli… - Sports Medicine, 2024 - Springer
Sex differences in physiological responses to various stressors, including exercise, have
been well documented. However, the specific impact of these differences on exposure to …

The psychophysiology of the sigh: I: The sigh from the physiological perspective

LJ Severs, E Vlemincx, JM Ramirez - Biological psychology, 2022 - Elsevier
Breathing is composed of multiple, distinct behaviors that are bidirectionally regulated
through autonomic and voluntary mechanisms. One behavioral component is the sigh …

Experimental models to study end-organ morbidity in sleep apnea: lessons learned and future directions

R Farré, I Almendros, MÁ Martínez-García… - International Journal of …, 2022 - mdpi.com
Sleep apnea (SA) is a very prevalent sleep breathing disorder mainly characterized by
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …

Cardiovascular and respiratory profiles during the sleep–wake cycle of rats previously submitted to chronic intermittent hypoxia

DS Bazilio, LGH Bonagamba… - Experimental …, 2019 - Wiley Online Library
New Findings What is the central question of this study? Chronic intermittent hypoxia (CIH)
causes increased arterial pressure (AP), sympathetic overactivity and changes in expiratory …

The protective role of SOD1 overexpression in central mediation of bradycardia following chronic intermittent hypoxia in mice

J Chen, H Gu, RD Wurster… - American Journal of …, 2021 - journals.physiology.org
Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder that is associated with
many cardiovascular complications. Similar to OSA, chronic intermittent hypoxia (CIH)(a …

Advances in cellular and integrative control of oxygen homeostasis within the central nervous system

JM Ramirez, LJ Severs, SC Ramirez… - The Journal of …, 2018 - Wiley Online Library
Mammals must continuously regulate the levels of O2 and CO2, which is particularly
important for the brain. Failure to maintain adequate O2/CO2 homeostasis has been …

Beat-to-beat blood pressure variability in patients with obstructive sleep apnea

A Pal, F Martinez, AP Aguila, MA Akey… - Journal of Clinical …, 2021 - jcsm.aasm.org
Study Objectives: Cardiovascular comorbidities in obstructive sleep apnea (OSA) are difficult
to treat, perhaps due to autonomic dysfunction. We assessed beat-to-beat blood pressure …

Chemoreflex sensitization occurs in both male and female rats during recovery from acute lung injury

K Kamra, IH Zucker, HD Schultz, HJ Wang - Frontiers in Physiology, 2024 - frontiersin.org
Introduction Sex-specific patterns in respiratory conditions, such as asthma, COPD, cystic
fibrosis, obstructive sleep apnea, and idiopathic pulmonary fibrosis, have been previously …

Systematic reviews and meta-analyses in animal model research: as necessary, and with similar pros and cons, as in patient research

R Farré, MA Martínez-García… - European Respiratory …, 2022 - Eur Respiratory Soc
Systematic reviews and meta-analyses (SRMAs) are very useful tools for evaluating the
status of research on a given topic in medical sciences [1, 2]. Although SRMAs are primarily …

Sex differences in the effect of acute intermittent hypoxia on respiratory modulation of sympathetic activity

JS Edmunds, CL Ivie, EP Ott… - American Journal …, 2021 - journals.physiology.org
Sex-related differences in respiratory modulation of sympathetic activity have been observed
in rodent models of sleep apnea [intermittent hypoxia (IH)]. In light of sex disparities in the …