Natural product triterpenoids and their semi-synthetic derivatives with potential anticancer activity

Y Ren, AD Kinghorn - Planta Medica, 2019 - thieme-connect.com
Triterpenoids are distributed widely in higher plants and are of interest because of their
structural diversity and broad range of bioactivities. In particular, there is a very large …

Phytochemistry of ginsenosides: Recent advancements and emerging roles

P Chopra, H Chhillar, YJ Kim, IH Jo… - Critical Reviews in …, 2023 - Taylor & Francis
Ginsenosides, a group of tetracyclic saponins, accounts for the nutraceutical and
pharmaceutical relevance of the ginseng (Panax sp.) herb. Owing to the associated …

Colon-Targeting Angelica sinensis Polysaccharide Nanoparticles with Dual Responsiveness for Alleviation of Ulcerative Colitis

Y Xu, BW Zhu, R Sun, X Li, D Wu… - ACS Applied Materials & …, 2023 - ACS Publications
Intestinal immune dysfunction and gut microbiota dysbiosis are critically causative factors in
the pathogenesis of ulcerative colitis (UC); however, the current first-line drugs for UC …

Glycogen-based pH and redox sensitive nanoparticles with ginsenoside Rh2 for effective treatment of ulcerative colitis

Y Xu, BW Zhu, X Li, YF Li, XM Ye, JN Hu - Biomaterials, 2022 - Elsevier
The purpose of this study is to construct a pH and redox sensitive nanoparticle to effectively
deliver ginsenoside Rh 2 for the treatment of ulcerative colitis (UC). Herein, glycogen was …

Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells

Q Wu, J Deng, D Fan, Z Duan, C Zhu, R Fu… - Biochemical …, 2018 - Elsevier
The use of ginsenosides in cancer therapy has been intensively investigated. The
ginsenoside Rh4 (Rh4), a rare saponin obtained from Panax notoginseng, dissolves in …

The structural characteristics of an acid-soluble polysaccharide from Grifola frondosa and its antitumor effects on H22-bearing mice

J Yu, H Ji, C Liu, A Liu - International Journal of Biological Macromolecules, 2020 - Elsevier
The edible mushroom G. frondosa has been used as a kind of functional food for the
prevention and therapy of various diseases in Asian countries. In the present work, a novel …

Effect of chitosan oligosaccharide-conjugated selenium on improving immune function and blocking gastric cancer growth

Z Jiang, J Chi, H Li, Y Wang, W Liu, B Han - European Journal of …, 2021 - Elsevier
Selenium (Se) is a potential chemopreventive or chemotherapeutic agent against malignant
tumor. Selenium-oligosaccharides are important selenium source of dietary …

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model

Y Liu, D Fan - Food & function, 2018 - pubs.rsc.org
Breast cancer is the most frequently diagnosed cancer and has become the main cause of
cancer-related death among women worldwide. Traditional chemotherapy for breast cancer …

Ovotransferrin ameliorates the dysbiosis of immunomodulatory function and intestinal microbiota induced by cyclophosphamide

G Zhu, Y Jiang, Y Yao, N Wu, J Luo, M Hu, Y Tu… - Food & function, 2019 - pubs.rsc.org
In this study, the regulative effects of ovotransferrin (OVT) on immunomodulatory function
and intestinal microbial dysbiosis in a mouse model injected with cyclophosphamide (CP) …

Functional polysaccharide Lentinan suppresses human breast cancer growth via inducing autophagy and caspase-7-mediated apoptosis

W Li, J Wang, H Hu, Q Li, Y Liu, K Wang - Journal of Functional Foods, 2018 - Elsevier
The aim of this study was to evaluate the direct antitumor activity of edible fungal
polysaccharide Lentinan, rather than as a host defence potentiator, on human breast cancer …