[HTML][HTML] The crosstalk between microbiome and mitochondrial homeostasis in neurodegeneration

F Borbolis, E Mytilinaiou, K Palikaras - Cells, 2023 - mdpi.com
Mitochondria are highly dynamic organelles that serve as the primary cellular energy-
generating system. Apart from ATP production, they are essential for many biological …

[HTML][HTML] Lactic acid bacteria (LAB) and neuroprotection, what is new? An up-to-date systematic review

N Abd Mutalib, SA Syed Mohamad, NA Jusril… - Pharmaceuticals, 2023 - mdpi.com
Background: In recent years, the potential role of probiotics has become prominent in the
discoveries of neurotherapy against neurodegenerative diseases, such as Alzheimer's and …

[HTML][HTML] Effects of tempeh probiotics on elderly with cognitive impairment

YS Handajani, Y Turana, Y Yogiara… - Frontiers in Aging …, 2022 - frontiersin.org
Introduction Oral consumption of probiotics can alter Gut Microbiota by causing changes in
the production of probiotic derivatives. Therefore, by utilizing Gut-Brain-Axis (GBA) …

The synergistic effect of nanocurcumin and donepezil on Alzheimer's via PI3K/AKT/GSK-3β pathway modulating

DM Beltagy, NF Nawar, TM Mohamed… - Prostaglandins & Other …, 2024 - Elsevier
Alzheimer's disease (AD) hallmarks include amyloid-βeta (Aβ) and tau proteins aggregates,
neurite degeneration, microglial activation with cognitive impairment. Phosphatidylinositol-3 …

Synergistic effect of spermidine and ciprofloxacin against Alzheimer's disease in male rat via ferroptosis modulation

MAM Youssef, TM Mohamed, AA Bakry… - International Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is a prevalent form of neurodegenerative disease with a complex
pathophysiology that remains not fully understood, and the exact mechanism of …

[HTML][HTML] Microbiota–gut–brain axis and related therapeutics in Alzheimer's disease: prospects for multitherapy and inflammation control

J Li, F Zhang, L Zhao, C Dong - Reviews in the Neurosciences, 2023 - degruyter.com
Alzheimer's disease (AD) is the most common type of dementia in the elderly and causes
neurodegeneration, leading to memory loss, behavioral disorder, and psychiatric …

Neuronal control of microglia through the mitochondria

AR Pereira-Santos, E Candeias, JD Magalhães… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The microbial toxin β-N-methylamino-L-alanine (BMAA), which is derived from
cyanobacteria, targets neuronal mitochondria, leading to the activation of neuronal innate …

The beneficial effect of probiotics supplementation on penicillin-induced focal seizure in rats

N Kızılaslan, O Sumbul, H Aygun - Neurochemical Research, 2022 - Springer
The focal epilepsy is a chronic neurological brain disorder which affects millions of people in
the world. There is emerging evidence that changes in the gut microbiota may have effects …

Ameliorative anti-coagulant, anti-oxidative and anti-ferroptotic activities of nanocurcumin and donepezil on coagulation, oxidation and ferroptosis in Alzheimer's …

NF Nawar, DM Beltagy, TM Mohamed… - Toxicology …, 2024 - academic.oup.com
Alzheimer's disease (ad) is a neurological condition that worsens over time and is
characterized by the buildup of amyloid (Aβ) plaques in the brain parenchyma …

Anti-oxidant activity of coenzyme Q10 against AlCl3/D-galactose in albino rat induced cognitive dysfunctions: Behavioral, biochemical, and BACE-1/GSK-3β …

NF Nawar, DM Beltagy, TM Mohamed… - Toxicology …, 2024 - academic.oup.com
The relationship between amyloid beta (Aβ) and oxidative stress (OS), both prominent
factors in Alzheimer's disease-related neural degeneration, is deeply interconnected. The …