Clostridioides difficile phage biology and application

J Heuler, LC Fortier, X Sun - FEMS Microbiology Reviews, 2021 - academic.oup.com
Clostridium difficile, now reclassified as Clostridioides difficile, is the causative agent of C.
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …

Development and Implementation of Whole Genome Sequencing-Based Typing Schemes for Clostridioides difficile

S Janezic, M Rupnik - Frontiers in Public Health, 2019 - frontiersin.org
Clostridioides difficile is an important nosocomial pathogen increasingly observed in the
community and in different non-human reservoirs. The epidemiology and transmissibility of …

Genomic Determination of Relative Risks for Clostridioides difficile Infection From Asymptomatic Carriage in Intensive Care Unit Patients

J Worley, ML Delaney, CK Cummins… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Clostridioides difficile infections (CDIs) are among the most prevalent
hospital-associated infections (HAIs), particularly for intensive care unit (ICU) patients. The …

A local-scale One Health genomic surveillance of Clostridioides difficile demonstrates highly related strains from humans, canines, and the environment

CHD Williamson, CC Roe, J Terriquez… - Microbial …, 2023 - microbiologyresearch.org
Although infections caused by Clostridioides difficile have historically been attributed to
hospital acquisition, growing evidence supports the role of community acquisition in C …

Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia

M Muñoz, D Restrepo-Montoya, N Kumar, G Iraola… - Scientific Reports, 2019 - nature.com
Clostridium difficile, the causal agent of antibiotic-associated diarrhea, has a complex
epidemiology poorly studied in Latin America. We performed a robust genomic and …

K-mer based prediction of Clostridioides difficile relatedness and ribotypes

MP Moore, MH Wilcox, AS Walker… - Microbial …, 2022 - microbiologyresearch.org
Comparative analysis of Clostridioides difficile whole-genome sequencing (WGS) data
enables fine scaled investigation of transmission and is increasingly becoming part of …

Development and Implementation of Whole Genome Sequencing-Based Typing Schemes for Clostridioides

S Janezic, M Rupnik - Pathogen Genomics: Empowering …, 2020 - books.google.com
(frequently called core genome or whole genome MLST, cgMLST, or wgMLST). SNV
analysis currently provides the ultimate resolution, however, typing nomenclature and …