Breast cancer: a molecularly heterogenous disease needing subtype-specific treatments
U Testa, G Castelli, E Pelosi - Medical Sciences, 2020 - mdpi.com
Breast cancer is the most commonly occurring cancer in women. There were over two-
million new cases in world in 2018. It is the second leading cause of death from cancer in …
million new cases in world in 2018. It is the second leading cause of death from cancer in …
[HTML][HTML] Histological types of breast cancer: how special are they?
B Weigelt, FC Geyer, JS Reis-Filho - Molecular oncology, 2010 - Elsevier
Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …
distinctive histological and biological features, clinical presentations and behaviours and …
Molecular analysis of TCGA breast cancer histologic types
Breast cancer is classified into multiple distinct histologic types, and many of the rarer types
have limited characterization. Here, we extend The Cancer Genome Atlas Breast Cancer …
have limited characterization. Here, we extend The Cancer Genome Atlas Breast Cancer …
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
B Weigelt, FL Baehner… - The Journal of Pathology …, 2010 - Wiley Online Library
In the last decade, the development of microarrays and the ability to perform massively
parallel gene expression analysis of human tumours were received with great excitement by …
parallel gene expression analysis of human tumours were received with great excitement by …
Histological and molecular types of breast cancer: is there a unifying taxonomy?
B Weigelt, JS Reis-Filho - Nature reviews Clinical oncology, 2009 - nature.com
Breast cancer is a complex and heterogeneous disease, comprising multiple tumor entities
associated with distinctive histological patterns and different biological features and clinical …
associated with distinctive histological patterns and different biological features and clinical …
Refinement of breast cancer classification by molecular characterization of histological special types
B Weigelt, HM Horlings, B Kreike… - The Journal of …, 2008 - Wiley Online Library
Most invasive breast cancers are classified as invasive ductal carcinoma not otherwise
specified (IDC NOS), whereas about 25% are defined as histological 'special types'. These …
specified (IDC NOS), whereas about 25% are defined as histological 'special types'. These …
[HTML][HTML] β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
FC Geyer, M Lacroix-Triki, K Savage, M Arnedos… - Modern pathology, 2011 - Elsevier
Aberrant β-catenin expression as determined by assessment of its subcellular localization
constitutes a surrogate marker of Wnt signalling pathway activation and has been reported …
constitutes a surrogate marker of Wnt signalling pathway activation and has been reported …
SF3B1 mutations constitute a novel therapeutic target in breast cancer
SL Maguire, A Leonidou, P Wai… - The Journal of …, 2015 - Wiley Online Library
Mutations in genes encoding proteins involved in RNA splicing have been found to occur at
relatively high frequencies in several tumour types including myelodysplastic syndromes …
relatively high frequencies in several tumour types including myelodysplastic syndromes …
Breast cancer—one term, many entities?
Breast cancer, rather than constituting a monolithic entity, comprises heterogeneous tumors
with different clinical characteristics, disease courses, and responses to specific treatments …
with different clinical characteristics, disease courses, and responses to specific treatments …
Molecular classification of breast cancer: what the pathologist needs to know
EA Rakha, AR Green - Pathology, 2017 - Elsevier
Breast cancer is a heterogeneous disease featuring distinct histological, molecular and
clinical phenotypes. Although traditional classification systems utilising clinicopathological …
clinical phenotypes. Although traditional classification systems utilising clinicopathological …