[HTML][HTML] Sex differences in immunity to viral infections

H Jacobsen, SL Klein - Frontiers in immunology, 2021 - frontiersin.org
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences
in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias …

[HTML][HTML] Sex differences in immune responses

SL Klein, KL Flanagan - Nature Reviews Immunology, 2016 - nature.com
Males and females differ in their immunological responses to foreign and self-antigens and
show distinctions in innate and adaptive immune responses. Certain immunological sex …

[HTML][HTML] Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction

MP Piccinni, R Raghupathy, S Saito… - Frontiers in …, 2021 - frontiersin.org
Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …

Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Chronic inflammatory lesions of the placenta are characterized by the infiltration of the organ
by lymphocytes, plasma cells, and/or macrophages and may result from infections (viral …

Sex differences in immune responses: Hormonal effects, antagonistic selection, and evolutionary consequences

J Roved, H Westerdahl, D Hasselquist - Hormones and behavior, 2017 - Elsevier
Males and females differ in both parasite load and the strength of immune responses and
these effects have been verified in humans and other vertebrates. Sex hormones act as …

Physiological and molecular determinants of embryo implantation

S Zhang, H Lin, S Kong, S Wang, H Wang… - Molecular aspects of …, 2013 - Elsevier
Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

Sex and gender differences in bacterial infections

SP Dias, MC Brouwer, D van de Beek - Infection and Immunity, 2022 - Am Soc Microbiol
There is a growing awareness of the importance of sex and gender in medicine and
research. Women typically have stronger immune responses to self and foreign antigens …

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

H Renz, P Brandtzaeg, M Hornef - Nature Reviews Immunology, 2012 - nature.com
The mucosal surfaces of the gut and airways have important barrier functions and regulate
the induction of immunological tolerance. The rapidly increasing incidence of chronic …

[HTML][HTML] Mechanisms of fetal T cell tolerance and immune regulation

E Rackaityte, J Halkias - Frontiers in immunology, 2020 - frontiersin.org
The developing human fetus generates both tolerogenic and protective immune responses
in response to the unique requirements of gestation. Thus, a successful human pregnancy …

Sex affects immunity

LM Pennell, CL Galligan, EN Fish - Journal of autoimmunity, 2012 - Elsevier
Sex based differences in immune responses, affecting both the innate and adaptive immune
responses, contribute to differences in the pathogenesis of infectious diseases in males and …