Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

The Role of Macrophages in Staphylococcus aureus Infection

GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

Clinical significance and pathogenesis of staphylococcal small colony variants in persistent infections

BC Kahl, K Becker, B Löffler - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Small colony variants (SCVs) were first described more than 100 years ago for
Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago …

Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis

J Josse, F Velard, SC Gangloff - Frontiers in cellular and infection …, 2015 - frontiersin.org
Bone cells, namely osteoblasts and osteoclasts work in concert and are responsible for
bone extracellular matrix formation and resorption. This homeostasis is, in part, altered …

Phenol-soluble modulins–critical determinants of staphylococcal virulence

GYC Cheung, HS Joo, SS Chatterjee… - FEMS microbiology …, 2014 - academic.oup.com
Phenol-soluble modulins (PSMs) are a recently discovered family of amphipathic, alpha-
helical peptides that have multiple roles in staphylococcal pathogenesis and contribute to a …

Staphylococcal trafficking and infection—from 'nose to gut'and back

EJM Raineri, D Altulea… - FEMS microbiology …, 2022 - academic.oup.com
Staphylococcus aureus is an opportunistic human pathogen, which is a leading cause of
infections worldwide. The challenge in treating S. aureus infection is linked to the …

Inside job: Staphylococcus aureus host-pathogen interactions

J Horn, K Stelzner, T Rudel, M Fraunholz - International Journal of Medical …, 2018 - Elsevier
Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of
diseases. Recent research established that once phagocytosed by neutrophils and …

Identification and treatment of the Staphylococcus aureus reservoir in vivo

BGJ Surewaard, JF Deniset, FJ Zemp… - Journal of Experimental …, 2016 - rupress.org
Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is reaching epidemic
proportions causing morbidity, mortality, and chronic disease due to relapses, suggesting an …

[HTML][HTML] The role of functional amyloids in bacterial virulence

N Van Gerven, SE Van der Verren, DM Reiter… - Journal of molecular …, 2018 - Elsevier
Amyloid fibrils are best known as a product of human and animal protein misfolding
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …

Intracellular replication of Staphylococcus aureus in mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

RS Flannagan, B Heit, DE Heinrichs - Cellular microbiology, 2016 - Wiley Online Library
The success of Staphylococcus aureus as a pathogen is partly attributable to its ability to
thwart host innate immune responses, which includes resisting the antimicrobial functions of …