Lipopolysaccharide recognition in the crossroads of TLR4 and caspase-4/11 mediated inflammatory pathways

A Zamyatina, H Heine - Frontiers in Immunology, 2020 - frontiersin.org
The innate immune response to lipopolysaccharide is essential for host defense against
Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is …

Lipopolysaccharide modification in Gram-negative bacteria during chronic infection

RF Maldonado, I Sá-Correia… - FEMS microbiology …, 2016 - academic.oup.com
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer
membrane that plays a key role in host–pathogen interactions with the innate immune …

[图书][B] Molecular detection of human bacterial pathogens

D Liu - 2011 - books.google.com
As more original molecular protocols and subsequent modifications are described in the
literature, it has become difficult for those not directly involved in the development of these …

Extreme Antimicrobial Peptide and Polymyxin B Resistance in the Genus Burkholderia

SA Loutet, MA Valvano - Frontiers in cellular and infection …, 2011 - frontiersin.org
Cationic antimicrobial peptides and polymyxins are a group of naturally occurring antibiotics
that can also possess immunomodulatory activities. They are considered a new source of …

Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia

MA Hamad, F Di Lorenzo, A Molinaro… - Molecular …, 2012 - Wiley Online Library
One common mechanism of resistance against antimicrobial peptides in Gram‐negative
bacteria is the addition of 4‐amino‐4‐deoxy‐l‐arabinose (l‐Ara4N) to the …

Fullerene sugar balls: a new class of biologically active fullerene derivatives

I Nierengarten, JF Nierengarten - Chemistry–An Asian Journal, 2014 - Wiley Online Library
Among the large variety of bioactive C60 derivatives, fullerene derivatives substituted with
sugar residues, that is, glycofullerenes, are of particular interest. The sugar residues are not …

Structural characterization of bacterial lipopolysaccharides with mass spectrometry and on‐and off‐line separation techniques

A Kilár, Á Dörnyei, B Kocsis - Mass spectrometry reviews, 2013 - Wiley Online Library
The focus of this review is the application of mass spectrometry to the structural
characterization of bacterial lipopolysaccharides (LPSs), also referred to as “endotoxins,” …

Pyroptotic and non‐pyroptotic effector functions of caspase‐11

A Abu Khweek, AO Amer - Immunological reviews, 2020 - Wiley Online Library
Innate immune cells, epithelial cells, and many other cell types are capable of detecting
infection or tissue injury, thus mounting regulated immune response. Inflammasomes are …

The inhibition of liposaccharide heptosyltransferase WaaC with multivalent glycosylated fullerenes: a new mode of glycosyltransferase inhibition

M Durka, K Buffet, J Iehl, M Holler… - … A European Journal, 2012 - Wiley Online Library
Abstract l, d‐Heptosides (l‐glycero‐d‐manno‐heptopyranoses) are found in important
bacterial glycolipids such as lipopolysaccharide (LPS), the biosynthesis of which is targeted …

Long-Term Colonization of the Cystic Fibrosis Lung by Burkholderia cepacia Complex Bacteria: Epidemiology, Clonal Variation, and Genome-Wide Expression …

CP Coutinho, SC Dos Santos, A Madeira… - Frontiers in cellular …, 2011 - frontiersin.org
Long-term respiratory infections with Burkholderia cepacia complex (Bcc) bacteria in cystic
fibrosis (CF) patients generally lead to a more rapid decline in lung function and, in some …