Tyrosine, phenylalanine and tryptophan are the three aromatic amino acids (AAA) involved
in protein synthesis. These amino acids and their metabolism are linked to the synthesis of a …

One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

Sialic acids are structurally unique nine-carbon keto sugars occupying the interface between
the host and commensal or pathogenic microorganisms. An important function of host sialic …

This review provides an extensive summary of the effects of carbohydrate fluorination with
regard to changes in physical, chemical and biological properties with respect to regular …

Sialic acids are a family of negatively charged monosaccharides which are commonly
presented as the terminal residues in glycans of the glycoconjugates on eukaryotic cell …

The enzymatic hydrolysis of the glycosidic bond continues to gain importance, reflecting the
critically important roles complex glycans play in health and disease as well as the rekindled …

Sialidases are a large group of enzymes, the majority of which catalyses the cleavage of
terminal sialic acids from complex carbohydrates on glycoproteins or glycolipids. In the …

Glycoside hydrolases, the enzymes responsible for hydrolysis of the glycosidic bond in di-,
oligo-and polysaccharides, and glycoconjugates, are ubiquitous in Nature and fundamental …

Carbohydrates are ubiquitous in Nature and play vital roles in many biological systems.
Therefore the synthesis of carbohydrate-based compounds is of considerable interest for …

Enzymes that catalyse the synthesis and breakdown of glycosidic bonds account for 1–3%
of the proteins encoded by the genomes of most organisms. At the current rate, over 12 000 …