Water as the reaction medium in organic chemistry: from our worst enemy to our best friend

M Cortes-Clerget, J Yu, JRA Kincaid, P Walde… - Chemical …, 2021 - pubs.rsc.org
Water as the reaction medium in organic chemistry: from our worst enemy to our best friend -
Chemical Science (RSC Publishing) DOI:10.1039/D0SC06000C Royal Society of Chemistry …

Opportunities and challenges for combining chemo-and biocatalysis

F Rudroff, MD Mihovilovic, H Gröger, R Snajdrova… - Nature Catalysis, 2018 - nature.com
The past decade has seen a substantial increase in successful examples of the combination
of chemo-and biocatalysis for multistep syntheses. This is driven by obvious advantages …

Synthesis and transformations of NH‐sulfoximines

M Andresini, A Tota, L Degennaro… - … –A European Journal, 2021 - Wiley Online Library
Recent years have seen a marked increase in the occurrence of sulfoximines in the
chemical sciences, often presented as valuable motifs for medicinal chemistry. This has …

The hydrophobic effect applied to organic synthesis: recent synthetic chemistry “in water”

BH Lipshutz, S Ghorai… - Chemistry–A European …, 2018 - Wiley Online Library
Recent developments over the past few years in aqueous micellar catalysis are discussed.
Applications to problems in synthesis are highlighted, enabled by the use of surfactants that …

Bridging the gap between transition metal-and bio-catalysis via aqueous micellar catalysis

M Cortes-Clerget, N Akporji, J Zhou, F Gao… - Nature …, 2019 - nature.com
Previous studies have shown that aqueous solutions of designer surfactants enable a wide
variety of valuable transformations in synthetic organic chemistry. Since reactions take place …

Water-sculpting of a heterogeneous nanoparticle precatalyst for Mizoroki–Heck couplings under aqueous micellar catalysis conditions

H Pang, Y Hu, J Yu, F Gallou… - Journal of the American …, 2021 - ACS Publications
Powdery, spherical nanoparticles (NPs) containing ppm levels of palladium ligated by t-
Bu3P, derived from FeCl3, upon simple exposure to water undergo a remarkable alteration …

Soft and dispersed interface-rich aqueous systems that promote and guide chemical reactions

S Serrano-Luginbühl, K Ruiz-Mirazo… - Nature reviews …, 2018 - nature.com
Although aqueous solutions are considered to be sustainable, environmentally friendly
reaction media, their use is often limited by poor reactant solubility. This limitation can be …

Palladium-catalyzed micellar cross-couplings: An outlook

TN Ansari, F Gallou, S Handa - Coordination Chemistry Reviews, 2023 - Elsevier
In the last decades, cross-coupling approaches have been widely used to generate
structural diversity efficiently. Among various transition-metals, palladium has remained the …

Contemporary approaches for amide bond formation

P Acosta‐Guzmán, A Ojeda‐Porras… - Advanced Synthesis …, 2023 - Wiley Online Library
Amide bond construction has garnered significant interest in recent decades due to amides
being one of the most prevalent functional groups among bioactive molecules. Out of the …

Surfactant micellar and vesicle microenvironments and structures under synthetic organic conditions

H Peacock, SA Blum - Journal of the American Chemical Society, 2023 - ACS Publications
Fluorescence lifetime imaging microscopy (FLIM) reveals vesicle sizes, structures,
microenvironments, reagent partitioning, and system evolution with two chemical reactions …