Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …

Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …

Children's experiences and voices are underrepresented in academic literature and
professional practice around domestic violence and abuse. The project “Understanding …

There is increasing interest in childhood maltreatment as a potent stimulus that may alter
trajectories of brain development, induce epigenetic modifications and enhance risk for …

Patients with major depressive disorder (MDD) present with heterogeneous symptom
profiles, while neurobiological mechanisms are still largely unknown. Brain network studies …

The amygdala is vulnerable to stress-dependent disruptions in neural development. Animal
models have shown that stress increases dendritic arborization leading to larger amygdala …

Background: Childhood trauma subtypes sexual abuse, physical abuse, emotional
maltreatment, and neglect may have differential effects on the brain that persist into …